|
1
|
Primecap Management
Pasadena,
California
|
$370M
|
-$6.78M
|
-214,773
|
-3%
|
|
|
2
|
Baker Bros. Advisors
New York
|
$294M
|
-$9.59M
|
-303,984
|
-5%
|
|
|
3
|
|
$292M
|
+$4.79M
|
+151,868
|
+2%
|
|
|
4
|
RA Capital Management
Boston,
Massachusetts
|
$245M
|
-$10.9M
|
-345,655
|
-6%
|
|
|
5
|
|
$232M
|
-$3.55M
|
-112,607
|
-2%
|
|
|
6
|
Vanguard Group
Malvern,
Pennsylvania
|
$148M
|
+$6.7M
|
+212,370
|
+7%
|
|
|
7
|
NEA Management Company
Timonium,
Maryland
|
$134M
|
–
|
–
|
–
|
|
|
8
|
Frazier Life Sciences Management
Palo Alto,
California
|
$109M
|
–
|
–
|
–
|
|
|
9
|
Federated Hermes
Pittsburgh,
Pennsylvania
|
$106M
|
-$958K
|
-30,380
|
-1%
|
|
|
10
|
State Street
Boston,
Massachusetts
|
$101M
|
-$5.04M
|
-159,838
|
-7%
|
|
|
11
|
Perceptive Advisors
New York
|
$99M
|
+$55.9M
|
+1,773,282
|
+466%
|
|
|
12
|
Polar Capital Holdings
London,
United Kingdom
|
$80.4M
|
-$23.7M
|
-750,000
|
-30%
|
|
|
13
|
Commodore Capital
New York
|
$71.3M
|
-$16.6M
|
-525,000
|
-25%
|
|
|
14
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$70M
|
-$2.34M
|
-74,230
|
-5%
|
|
|
15
|
Pictet Asset Management
Carouge,
Switzerland
|
$53.5M
|
+$36.7M
|
+1,163,961
|
New
|
|
|
16
|
Geode Capital Management
Boston,
Massachusetts
|
$51.5M
|
+$2.34M
|
+74,072
|
+7%
|
|
|
17
|
Checkpoint Capital
San Francisco,
California
|
$33.6M
|
+$23M
|
+730,000
|
New
|
|
|
18
|
Janus Henderson Group
London,
|
$28.6M
|
-$14M
|
-443,853
|
-42%
|
|
|
19
|
Opaleye Management
Boston,
Massachusetts
|
$28M
|
-$1.36M
|
-43,000
|
-7%
|
|
|
20
|
Driehaus Capital Management
Chicago,
Illinois
|
$27.5M
|
+$10.2M
|
+324,381
|
+118%
|
|
|
21
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$26.3M
|
+$11.4M
|
+361,945
|
+172%
|
|
|
22
|
Cormorant Asset Management
Boston,
Massachusetts
|
$25.3M
|
-$9.46M
|
-300,000
|
-35%
|
|
|
23
|
|
$24.7M
|
-$1.48M
|
-47,000
|
-8%
|
|
|
24
|
Fidelity Investments
Boston,
Massachusetts
|
$24.3M
|
-$10.7M
|
-339,344
|
-39%
|
|
|
25
|
Northern Trust
Chicago,
Illinois
|
$23M
|
-$92.4K
|
-2,928
|
-0.6%
|
|
