|
1
|
RA Capital Management
Boston,
Massachusetts
|
$740M
|
–
|
–
|
–
|
|
|
2
|
|
$684M
|
-$7.26M
|
-80,249
|
-1%
|
|
|
3
|
Baker Bros. Advisors
New York
|
$622M
|
–
|
–
|
–
|
|
|
4
|
Primecap Management
Pasadena,
California
|
$352M
|
-$22.5M
|
-248,656
|
-7%
|
|
|
5
|
Vanguard Portfolio Management
Malvern,
Pennsylvania
|
$348M
|
+$8.7M
|
+96,177
|
+3%
|
|
|
6
|
Vanguard Capital Management
Malvern,
Pennsylvania
|
$334M
|
+$3.45M
|
+38,152
|
+1%
|
|
|
7
|
|
$292M
|
+$99.4M
|
+1,099,102
|
+71%
|
|
|
8
|
Perceptive Advisors
New York
|
$287M
|
+$19.2M
|
+212,500
|
+9%
|
|
|
9
|
State Street
Boston,
Massachusetts
|
$286M
|
+$27.3M
|
+301,678
|
+13%
|
|
|
10
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$285M
|
+$82.4M
|
+911,295
|
+55%
|
|
|
11
|
Westfield Capital Management
Boston,
Massachusetts
|
$245M
|
+$25.3M
|
+279,472
|
+14%
|
|
|
12
|
|
$236M
|
+$14.6M
|
+161,070
|
+8%
|
|
|
13
|
Federated Hermes
Pittsburgh,
Pennsylvania
|
$198M
|
+$45.2M
|
+499,413
|
+39%
|
|
|
14
|
Polar Capital Holdings
London,
United Kingdom
|
$185M
|
+$4.34M
|
+48,046
|
+3%
|
|
|
15
|
Geode Capital Management
Boston,
Massachusetts
|
$170M
|
+$10.6M
|
+117,429
|
+8%
|
|
|
16
|
Capital Research Global Investors
Los Angeles,
California
|
$170M
|
+$37.7M
|
+416,843
|
+37%
|
|
|
17
|
Citadel Advisors
Miami,
Florida
|
$140M
|
-$14M
|
-154,967
|
-11%
|
|
|
18
|
Checkpoint Capital
San Francisco,
California
|
$132M
|
-$3.73M
|
-41,200
|
-3%
|
|
|
19
|
Siren LLC
Greenwich,
Connecticut
|
$126M
|
+$37.1M
|
+410,764
|
+57%
|
|
|
20
|
|
$123M
|
+$36.9M
|
+408,262
|
+58%
|
|
|
21
|
Fidelity Investments
Boston,
Massachusetts
|
$114M
|
-$60M
|
-663,831
|
-39%
|
|
|
22
|
Pictet Asset Management
Carouge,
Switzerland
|
$106M
|
+$26.3M
|
+290,739
|
+44%
|
|
|
23
|
|
$103M
|
+$83.7M
|
+925,490
|
New
|
|
|
24
|
Woodline Partners
San Francisco,
California
|
$84.3M
|
–
|
–
|
–
|
|
|
25
|
AllianceBernstein
Nashville,
Tennessee
|
$77.8M
|
-$1.42M
|
-15,690
|
-2%
|
|
