RYTM icon

Rhythm Pharmaceuticals
RYTM

Overview Fund Activity

225 hedge funds and large institutions have $4.2B invested in Rhythm Pharmaceuticals in 2025 Q2 according to their latest regulatory filings, with 34 funds opening new positions, 92 increasing their positions, 73 reducing their positions, and 34 closing their positions.

Holders
225
Holders Change
-3
Holders Change %
-1.32%
% of All Funds
3.02%
Holding in Top 10
10
Holding in Top 10 Change
+3
Holding in Top 10 Change %
+42.86%
% of All Funds
0.13%
New
34
Increased
92
Reduced
73
Closed
34
Calls
$9.98M
Puts
$28.3M
Net Calls
-$18.3M
Net Calls Change
-$36.3M

Top Buyers

1
PCH
1
Polar Capital Holdings
United Kingdom
$79M
2
JPMorgan Chase & Co
2
JPMorgan Chase & Co
New York
$49.5M
3
WP
3
Woodline Partners
California
$32.5M
4
Adage Capital Partners
4
Adage Capital Partners
Massachusetts
$21.5M
5
ClearBridge Investments
5
ClearBridge Investments
New York
$19.7M

Top Sellers

1
Primecap Management
1
Primecap Management
California
$308M
2
BlackRock
2
BlackRock
New York
$396M
3
FLSM
3
Frazier Life Sciences Management
California
$0
4
RCM
4
RA Capital Management
Massachusetts
$351M
5
Balyasny Asset Management
5
Balyasny Asset Management
Illinois
$3.42M
Name Market Value Shares Shares
Change 		Shares
Change %
BlackRock
1
BlackRock
New York
$396M 6,267,538 -587,217 -9%
BBA
2
Baker Bros. Advisors
New York
$354M 5,604,483 – –
RCM
3
RA Capital Management
Massachusetts
$351M 5,561,359 -523,053 -9%
Primecap Management
4
Primecap Management
California
$308M 4,878,037 -909,285 -16%
Vanguard Group
5
Vanguard Group
Pennsylvania
$227M 3,589,114 +144,188 +4%
NMC
6
NEA Management Company
Maryland
$184M 2,909,956 – –
PA
7
Perceptive Advisors
New York
$153M 2,418,299 -130,146 -5%
Fidelity Investments
8
Fidelity Investments
Massachusetts
$123M 1,953,441 +265,066 +16%
State Street
9
State Street
Massachusetts
$121M 1,907,601 -63,132 -3%
Goldman Sachs
10
Goldman Sachs
New York
$110M 1,733,722 +95,814 +6%
Federated Hermes
11
Federated Hermes
Pennsylvania
$107M 1,686,494 +94,623 +6%
Westfield Capital Management
12
Westfield Capital Management
Massachusetts
$103M 1,629,468 +288,376 +22%
Janus Henderson Group
13
Janus Henderson Group
United Kingdom
$89.3M 1,411,902 -243,448 -15%
T. Rowe Price Associates
14
T. Rowe Price Associates
Maryland
$84.8M 1,341,392 +142,339 +12%
Geode Capital Management
15
Geode Capital Management
Massachusetts
$82.9M 1,311,253 +24,085 +2%
DCM
16
Driehaus Capital Management
Illinois
$80.2M 1,269,952 -188,070 -13%
PCH
17
Polar Capital Holdings
United Kingdom
$79M 1,250,870 +750,870 +150%
CC
18
Checkpoint Capital
California
$67M 1,060,000 +152,760 +17%
Alkeon Capital Management
19
Alkeon Capital Management
New York
$64.3M 1,017,700 +200,000 +24%
RSCM
20
Rock Springs Capital Management
Maryland
$54.4M 861,153 +26,965 +3%
JPMorgan Chase & Co
21
JPMorgan Chase & Co
New York
$49.5M 783,559 +639,919 +446%
Loomis, Sayles & Company
22
Loomis, Sayles & Company
Massachusetts
$37.4M 591,454 -14,310 -2%
SI
23
Sofinnova Investments
California
$37M 586,010 +139,171 +31%
Franklin Resources
24
Franklin Resources
California
$34.4M 543,802 +217,642 +67%
HRCM
25
Hood River Capital Management
Florida
$34.4M 543,688 -115,743 -18%
1
2 3 4 5