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Rhythm Pharmaceuticals
RYTM

Overview Fund Activity

167 hedge funds and large institutions have $2.95B invested in Rhythm Pharmaceuticals in 2024 Q1 according to their latest regulatory filings, with 25 funds opening new positions, 63 increasing their positions, 54 reducing their positions, and 26 closing their positions.

Holders
167
Holders Change
-1
Holders Change %
-0.6%
% of All Funds
2.42%
Holding in Top 10
9
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-10%
% of All Funds
0.13%
New
25
Increased
63
Reduced
54
Closed
26
Calls
$42.6M
Puts
$11.2M
Net Calls
+$31.4M
Net Calls Change
-$15.5M

Top Buyers

1
PA
1
Perceptive Advisors
New York
$142M
2
State Street
2
State Street
Massachusetts
$131M
3
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
3
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
Ontario, Canada
$31.7M
4
Canada Pension Plan Investment Board
4
Canada Pension Plan Investment Board
Ontario, Canada
$25M
5
DCM
5
Driehaus Capital Management
Illinois
$37.1M

Top Sellers

1
Federated Hermes
1
Federated Hermes
Pennsylvania
$72M
2
VA
2
VR Adviser
New York
$0
3
Fidelity Investments
3
Fidelity Investments
Massachusetts
$1.26M
4
CC
4
Commodore Capital
New York
$45.5M
5
Primecap Management
5
Primecap Management
California
$336M
Name Market Value Shares Shares
Change 		Shares
Change %
Primecap Management
1
Primecap Management
California
$336M 7,747,591 -305,057 -4%
BlackRock
2
BlackRock
New York
$283M 6,529,646 +177,896 +3%
BBA
3
Baker Bros. Advisors
New York
$277M 6,398,365 – –
RCM
4
RA Capital Management
Massachusetts
$231M 5,330,412 – –
Goldman Sachs
5
Goldman Sachs
New York
$221M 5,111,601 +63,667 +1%
Vanguard Group
6
Vanguard Group
Pennsylvania
$143M 3,304,146 +77,208 +2%
PA
7
Perceptive Advisors
New York
$142M 3,268,579 +1,114,469 +52%
State Street
8
State Street
Massachusetts
$131M 3,013,838 +807,820 +37%
NMC
9
NEA Management Company
Maryland
$126M 2,909,956 – –
FLSM
10
Frazier Life Sciences Management
California
$94.9M 2,190,179 -181,125 -8%
Federated Hermes
11
Federated Hermes
Pennsylvania
$72M 1,661,097 -649,858 -28%
RSCM
12
Rock Springs Capital Management
Maryland
$66M 1,522,893 – –
PCH
13
Polar Capital Holdings
United Kingdom
$65M 1,500,000 -250,000 -14%
Pictet Asset Management
14
Pictet Asset Management
Switzerland
$52.5M 1,211,679 +47,718 +4%
Geode Capital Management
15
Geode Capital Management
Massachusetts
$51.2M 1,180,705 +61,576 +6%
CC
16
Commodore Capital
New York
$45.5M 1,050,000 -500,000 -32%
DCM
17
Driehaus Capital Management
Illinois
$37.1M 855,505 +256,600 +43%
CC
18
Checkpoint Capital
California
$35.8M 825,500 +95,500 +13%
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
19
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
Ontario, Canada
$31.7M 730,643 +578,800 +381%
O
20
OrbiMed
New York
$30.5M 704,842 +168,200 +31%
Janus Henderson Group
21
Janus Henderson Group
United Kingdom
$26.9M 621,427 -465 -0.1%
Canada Pension Plan Investment Board
22
Canada Pension Plan Investment Board
Ontario, Canada
$25M 577,000 +310,000 +116%
CAM
23
Cormorant Asset Management
Massachusetts
$23.8M 550,000 – –
OM
24
Opaleye Management
Massachusetts
$22.3M 515,000 -95,000 -16%
Northern Trust
25
Northern Trust
Illinois
$21.8M 502,855 +1,761 +0.4%
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