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Rhythm Pharmaceuticals
RYTM

Overview Fund Activity

203 hedge funds and large institutions have $3.63B invested in Rhythm Pharmaceuticals in 2024 Q4 according to their latest regulatory filings, with 53 funds opening new positions, 65 increasing their positions, 53 reducing their positions, and 24 closing their positions.

Holders
203
Holders Change
+28
Holders Change %
+16%
% of All Funds
2.7%
Holding in Top 10
11
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+10%
% of All Funds
0.15%
New
53
Increased
65
Reduced
53
Closed
24
Calls
$26.8M
Puts
$1.76M
Net Calls
+$25M
Net Calls Change
-$16.2M

Top Buyers

1
Janus Henderson Group
1
Janus Henderson Group
United Kingdom
$68.3M
2
Marshall Wace
2
Marshall Wace
United Kingdom
$38.8M
3
JPMorgan Chase & Co
3
JPMorgan Chase & Co
New York
$14.8M
4
UBS Group
4
UBS Group
Switzerland
$14.2M
5
SC
5
Stempoint Capital
New York
$11.6M

Top Sellers

1
Goldman Sachs
1
Goldman Sachs
New York
$101M
2
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
2
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
Ontario, Canada
$0
3
Primecap Management
3
Primecap Management
California
$368M
4
CC
4
Commodore Capital
New York
$0
5
FLSM
5
Frazier Life Sciences Management
California
$105M
Name Market Value Shares Shares
Change 		Shares
Change %
BlackRock
1
BlackRock
New York
$389M 6,950,715 +61,457 +0.9%
Primecap Management
2
Primecap Management
California
$368M 6,571,190 -645,721 -9%
RCM
3
RA Capital Management
Massachusetts
$341M 6,084,412 – –
BBA
4
Baker Bros. Advisors
New York
$341M 6,084,249 -314,117 -5%
PA
5
Perceptive Advisors
New York
$206M 3,680,473 +120,259 +3%
Vanguard Group
6
Vanguard Group
Pennsylvania
$193M 3,442,600 -5,311 -0.2%
NMC
7
NEA Management Company
Maryland
$163M 2,909,956 – –
FLSM
8
Frazier Life Sciences Management
California
$105M 1,869,808 -547,144 -23%
State Street
9
State Street
Massachusetts
$103M 1,840,870 -152,296 -8%
Goldman Sachs
10
Goldman Sachs
New York
$101M 1,812,206 -2,067,590 -53%
Federated Hermes
11
Federated Hermes
Pennsylvania
$86.7M 1,549,635 -114,265 -7%
PCH
12
Polar Capital Holdings
United Kingdom
$84M 1,500,000 – –
DCM
13
Driehaus Capital Management
Illinois
$72.3M 1,290,975 -8,515 -0.7%
Geode Capital Management
14
Geode Capital Management
Massachusetts
$70.3M 1,255,799 -389 -0%
Janus Henderson Group
15
Janus Henderson Group
United Kingdom
$68.3M 1,219,554 +621,432 +104%
Alkeon Capital Management
16
Alkeon Capital Management
New York
$65.4M 1,167,700 – –
RSCM
17
Rock Springs Capital Management
Maryland
$65.1M 1,162,718 -65,375 -5%
CC
18
Checkpoint Capital
California
$40.8M 727,982 +64,601 +10%
Marshall Wace
19
Marshall Wace
United Kingdom
$38.8M 692,803 +286,188 +70%
T. Rowe Price Associates
20
T. Rowe Price Associates
Maryland
$38.4M 685,152 +134,622 +24%
HRCM
21
Hood River Capital Management
Florida
$36M 643,691 +29,093 +5%
Loomis, Sayles & Company
22
Loomis, Sayles & Company
Massachusetts
$34.6M 618,485 -18,143 -3%
Morgan Stanley
23
Morgan Stanley
New York
$31.4M 560,087 +95,483 +21%
Northern Trust
24
Northern Trust
Illinois
$30.5M 545,314 +46,848 +9%
OM
25
Opaleye Management
Massachusetts
$28M 500,000 – –
1
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