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Rhythm Pharmaceuticals

203 hedge funds and large institutions have $3.63B invested in Rhythm Pharmaceuticals in 2024 Q4 according to their latest regulatory filings, with 52 funds opening new positions, 66 increasing their positions, 53 reducing their positions, and 24 closing their positions.

New
Increased
Maintained
Reduced
Closed

1,417% more call options, than puts

Call options by funds: $26.8M | Put options by funds: $1.76M

117% more first-time investments, than exits

New positions opened: 52 | Existing positions closed: 24

25% more repeat investments, than reductions

Existing positions increased: 66 | Existing positions reduced: 53

15% more funds holding

Funds holding: 176203 (+27)

10% more funds holding in top 10

Funds holding in top 10: 1011 (+1)

2% more capital invested

Capital invested by funds: $3.55B → $3.63B (+$88M)

5.12% less ownership

Funds ownership: 110.75%105.63% (-5.1%)

Holders
203
Holders Change
+27
Holders Change %
+15.34%
% of All Funds
2.67%
Holding in Top 10
11
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+10%
% of All Funds
0.14%
New
52
Increased
66
Reduced
53
Closed
24
Calls
$26.8M
Puts
$1.76M
Net Calls
+$25M
Net Calls Change
-$16.2M
Name Holding Trade Value Shares
Change
Change in
Stake
BlackRock
1
BlackRock
New York
$389M +$3.39M +61,457 +0.9%
Primecap Management
2
Primecap Management
California
$368M -$35.7M -645,721 -9%
RCM
3
RA Capital Management
Massachusetts
$341M
BBA
4
Baker Bros. Advisors
New York
$341M -$17.4M -314,117 -5%
PA
5
Perceptive Advisors
New York
$206M +$6.64M +120,259 +3%
Vanguard Group
6
Vanguard Group
Pennsylvania
$193M -$293K -5,311 -0.2%
NMC
7
NEA Management Company
Maryland
$163M
FLSM
8
Frazier Life Sciences Management
California
$105M -$30.2M -547,144 -23%
State Street
9
State Street
Massachusetts
$103M -$8.41M -152,296 -8%
Goldman Sachs
10
Goldman Sachs
New York
$101M -$114M -2,067,590 -53%
Federated Hermes
11
Federated Hermes
Pennsylvania
$86.7M -$6.31M -114,265 -7%
PCH
12
Polar Capital Holdings
United Kingdom
$84M
DCM
13
Driehaus Capital Management
Illinois
$72.3M -$470K -8,515 -0.7%
Geode Capital Management
14
Geode Capital Management
Massachusetts
$70.3M -$21.5K -389 -0%
Janus Henderson Group
15
Janus Henderson Group
United Kingdom
$68.3M +$34.3M +621,432 +104%
Alkeon Capital Management
16
Alkeon Capital Management
New York
$65.4M
RSCM
17
Rock Springs Capital Management
Maryland
$65.1M -$3.61M -65,375 -5%
CC
18
Checkpoint Capital
California
$40.8M +$3.57M +64,601 +10%
Marshall Wace
19
Marshall Wace
United Kingdom
$38.8M +$15.8M +286,188 +70%
T. Rowe Price Associates
20
T. Rowe Price Associates
Maryland
$38.4M +$7.44M +134,622 +24%
HRCM
21
Hood River Capital Management
Florida
$36M +$1.61M +29,093 +5%
Loomis, Sayles & Company
22
Loomis, Sayles & Company
Massachusetts
$34.6M -$1M -18,143 -3%
Morgan Stanley
23
Morgan Stanley
New York
$31.4M +$5.27M +95,483 +21%
Northern Trust
24
Northern Trust
Illinois
$30.5M +$2.59M +46,848 +9%
OM
25
Opaleye Management
Massachusetts
$28M

RYTM Hedge Fund Activity: Q4 2024 in Review

203 of the 7,592 institutional investors tracked by Wall St. Rank reported a position in Rhythm Pharmaceuticals (RYTM) for Q4 2024, worth a combined $3.63B — up 2.5% from $3.55B a quarter earlier.

Buyers outnumbered sellers: 52 funds opened new RYTM positions and 24 closed out — a net gain of 28 holders — while 66 added to existing stakes and 53 trimmed.

The largest buyer was Janus Henderson Group, adding an estimated $34.3M. The largest seller was Goldman Sachs, cutting an estimated $114M.

  • 203 institutional investors held Rhythm Pharmaceuticals (RYTM) as of Q4 2024, up from 176 in Q3 2024.
  • Funds reported $3.63B of Rhythm Pharmaceuticals stock for Q4 2024, up 2.5% quarter-over-quarter.
  • 52 funds opened new Rhythm Pharmaceuticals positions in Q4 2024 and 24 closed out, a net change of +28 holders.
  • The largest Rhythm Pharmaceuticals buyer in Q4 2024 was Janus Henderson Group, an estimated $34.3M added.
  • The largest Rhythm Pharmaceuticals seller in Q4 2024 was Goldman Sachs, an estimated $114M sold.

Based on aggregated 13F filings for Q4 2024.