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Rhythm Pharmaceuticals
RYTM

Overview Fund Activity

115 hedge funds and large institutions have $1.81B invested in Rhythm Pharmaceuticals in 2022 Q4 according to their latest regulatory filings, with 26 funds opening new positions, 42 increasing their positions, 28 reducing their positions, and 12 closing their positions.

Holders
115
Holders Change
+14
Holders Change %
+13.86%
% of All Funds
1.86%
Holding in Top 10
5
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-16.67%
% of All Funds
0.08%
New
26
Increased
42
Reduced
28
Closed
12
Calls
$15.5M
Puts
$12.9M
Net Calls
+$2.66M
Net Calls Change
-$18.2M

Top Buyers

1
PCH
1
Polar Capital Holdings
United Kingdom
$36.4M
2
Alkeon Capital Management
2
Alkeon Capital Management
New York
$65.2M
3
Susquehanna International Group
3
Susquehanna International Group
Pennsylvania
$20.2M
4
Goldman Sachs
4
Goldman Sachs
New York
$151M
5
Vanguard Group
5
Vanguard Group
Pennsylvania
$75.6M

Top Sellers

1
Janus Henderson Group
1
Janus Henderson Group
United Kingdom
$36.1M
2
Fidelity Investments
2
Fidelity Investments
Massachusetts
$22.5M
3
Walleye Capital
3
Walleye Capital
New York
$0
4
Primecap Management
4
Primecap Management
California
$201M
5
CSS
5
Cubist Systematic Strategies
Connecticut
$481K
Name Market Value Shares Shares
Change 		Shares
Change %
Primecap Management
1
Primecap Management
California
$201M 6,911,142 -115,750 -2%
BBA
2
Baker Bros. Advisors
New York
$185M 6,354,608 +291,906 +5%
Federated Hermes
3
Federated Hermes
Pennsylvania
$184M 6,304,482 -2,384 -0%
RCM
4
RA Capital Management
Massachusetts
$161M 5,516,067 +45,000 +0.8%
Goldman Sachs
5
Goldman Sachs
New York
$151M 5,201,792 +424,614 +9%
NMC
6
NEA Management Company
Maryland
$143M 4,909,956 -2,350 -0%
BlackRock
7
BlackRock
New York
$108M 3,723,714 +186,215 +5%
State Street
8
State Street
Massachusetts
$92.6M 3,180,698 +52,793 +2%
Vanguard Group
9
Vanguard Group
Pennsylvania
$75.6M 2,596,314 +362,042 +16%
Alkeon Capital Management
10
Alkeon Capital Management
New York
$65.2M 2,238,262 +533,262 +31%
FLSM
11
Frazier Life Sciences Management
California
$55.2M 1,894,000 – –
RSCM
12
Rock Springs Capital Management
Maryland
$51.3M 1,760,865 – –
PCH
13
Polar Capital Holdings
United Kingdom
$36.4M 1,250,000 +535,261 +75%
Janus Henderson Group
14
Janus Henderson Group
United Kingdom
$36.1M 1,240,153 -1,882,013 -60%
Fidelity Investments
15
Fidelity Investments
Massachusetts
$22.5M 773,028 -597,920 -44%
OM
16
Opaleye Management
Massachusetts
$21.4M 735,000 -75,000 -9%
Susquehanna International Group
17
Susquehanna International Group
Pennsylvania
$20.2M 694,042 +479,520 +224%
Assenagon Asset Management
18
Assenagon Asset Management
Luxembourg
$13.5M 463,516 -6,894 -1%
Geode Capital Management
19
Geode Capital Management
Massachusetts
$13.4M 458,510 +70,398 +18%
D.E. Shaw & Co
20
D.E. Shaw & Co
New York
$10.4M 355,530 +172,461 +94%
SB
21
Samsara BioCapital
California
$10.1M 345,293 – –
Invesco
22
Invesco
Georgia
$9.73M 334,273 +334,273 New
Rafferty Asset Management
23
Rafferty Asset Management
New York
$8.91M 306,013 +43,725 +17%
Citigroup
24
Citigroup
New York
$8.02M 275,561 +3,374 +1%
Bank of America
25
Bank of America
North Carolina
$7.75M 266,153 +47,744 +22%
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