|
1
|
Primecap Management
Pasadena,
California
|
$336M
|
-$13.4M
|
-305,057
|
-4%
|
|
|
2
|
|
$283M
|
+$7.79M
|
+177,896
|
+3%
|
|
|
3
|
Baker Bros. Advisors
New York
|
$277M
|
–
|
–
|
–
|
|
|
4
|
RA Capital Management
Boston,
Massachusetts
|
$231M
|
–
|
–
|
–
|
|
|
5
|
|
$221M
|
+$2.79M
|
+63,667
|
+1%
|
|
|
6
|
Vanguard Group
Malvern,
Pennsylvania
|
$143M
|
+$3.38M
|
+77,208
|
+2%
|
|
|
7
|
Perceptive Advisors
New York
|
$142M
|
+$48.8M
|
+1,114,469
|
+52%
|
|
|
8
|
State Street
Boston,
Massachusetts
|
$131M
|
+$35.4M
|
+807,820
|
+37%
|
|
|
9
|
NEA Management Company
Timonium,
Maryland
|
$126M
|
–
|
–
|
–
|
|
|
10
|
Frazier Life Sciences Management
Palo Alto,
California
|
$94.9M
|
-$7.93M
|
-181,125
|
-8%
|
|
|
11
|
Federated Hermes
Pittsburgh,
Pennsylvania
|
$72M
|
-$28.4M
|
-649,858
|
-28%
|
|
|
12
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$66M
|
–
|
–
|
–
|
|
|
13
|
Polar Capital Holdings
London,
United Kingdom
|
$65M
|
-$10.9M
|
-250,000
|
-14%
|
|
|
14
|
Pictet Asset Management
Carouge,
Switzerland
|
$52.5M
|
+$2.09M
|
+47,718
|
+4%
|
|
|
15
|
Geode Capital Management
Boston,
Massachusetts
|
$51.2M
|
+$2.69M
|
+61,576
|
+6%
|
|
|
16
|
Commodore Capital
New York
|
$45.5M
|
-$21.9M
|
-500,000
|
-32%
|
|
|
17
|
Driehaus Capital Management
Chicago,
Illinois
|
$37.1M
|
+$11.2M
|
+256,600
|
+43%
|
|
|
18
|
Checkpoint Capital
San Francisco,
California
|
$35.8M
|
+$4.18M
|
+95,500
|
+13%
|
|
|
19
|
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
Toronto,
Ontario, Canada
|
$31.7M
|
+$25.3M
|
+578,800
|
+381%
|
|
|
20
|
|
$30.5M
|
+$7.36M
|
+168,200
|
+31%
|
|
|
21
|
Janus Henderson Group
London,
|
$26.9M
|
-$20.4K
|
-465
|
-0.1%
|
|
|
22
|
Canada Pension Plan Investment Board
Toronto Ontario,
Ontario, Canada
|
$25M
|
+$13.6M
|
+310,000
|
+116%
|
|
|
23
|
Cormorant Asset Management
Boston,
Massachusetts
|
$23.8M
|
–
|
–
|
–
|
|
|
24
|
Opaleye Management
Boston,
Massachusetts
|
$22.3M
|
-$4.16M
|
-95,000
|
-16%
|
|
|
25
|
Northern Trust
Chicago,
Illinois
|
$21.8M
|
+$77.1K
|
+1,761
|
+0.4%
|
|
