|
1
|
Primecap Management
Pasadena,
California
|
$136M
|
+$17.5M
|
+696,169
|
+10%
|
|
|
2
|
Baker Bros. Advisors
New York
|
$116M
|
+$3.61M
|
+143,659
|
+2%
|
|
|
3
|
RA Capital Management
Boston,
Massachusetts
|
$98.4M
|
–
|
–
|
–
|
|
|
4
|
|
$94.7M
|
+$2.74M
|
+108,911
|
+2%
|
|
|
5
|
Federated Hermes
Pittsburgh,
Pennsylvania
|
$69.4M
|
-$60.6M
|
-2,412,799
|
-38%
|
|
|
6
|
|
$67.4M
|
+$1.43M
|
+56,885
|
+2%
|
|
|
7
|
NEA Management Company
Timonium,
Maryland
|
$51.9M
|
-$50.2M
|
-2,000,000
|
-41%
|
|
|
8
|
Vanguard Group
Malvern,
Pennsylvania
|
$47.2M
|
+$1.3M
|
+51,822
|
+2%
|
|
|
9
|
State Street
Boston,
Massachusetts
|
$46.6M
|
-$14.3M
|
-568,510
|
-18%
|
|
|
10
|
Frazier Life Sciences Management
Palo Alto,
California
|
$38.6M
|
+$6.8M
|
+270,739
|
+14%
|
|
|
11
|
Alkeon Capital Management
New York
|
$36M
|
-$5.58M
|
-222,296
|
-10%
|
|
|
12
|
Polar Capital Holdings
London,
United Kingdom
|
$31.2M
|
+$12.6M
|
+500,000
|
+40%
|
|
|
13
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$28.5M
|
-$4.11M
|
-163,742
|
-9%
|
|
|
14
|
Janus Henderson Group
London,
|
$19.6M
|
-$3.58M
|
-142,580
|
-11%
|
|
|
15
|
Susquehanna International Group
Bala Cynwyd,
Pennsylvania
|
$14M
|
+$2.27M
|
+90,513
|
+13%
|
|
|
16
|
Opaleye Management
Boston,
Massachusetts
|
$13.1M
|
–
|
–
|
–
|
|
|
17
|
Fidelity Investments
Boston,
Massachusetts
|
$12.5M
|
-$1.86M
|
-74,204
|
-10%
|
|
|
18
|
Assenagon Asset Management
Senningerberg,
Luxembourg
|
$11.8M
|
+$5.04M
|
+200,510
|
+43%
|
|
|
19
|
Millennium Management
New York
|
$9.76M
|
+$12.7M
|
+504,608
|
+1,193%
|
|
|
20
|
Geode Capital Management
Boston,
Massachusetts
|
$8.43M
|
+$358K
|
+14,251
|
+3%
|
|
|
21
|
Citadel Advisors
Miami,
Florida
|
$6.51M
|
+$7.39M
|
+294,342
|
+416%
|
|
|
22
|
Bank of America
Charlotte,
North Carolina
|
$6.42M
|
+$2.35M
|
+93,513
|
+35%
|
|
|
23
|
|
$6.24M
|
+$3.77M
|
+150,136
|
+75%
|
|
|
24
|
Samsara BioCapital
Palo Alto,
California
|
$6.16M
|
–
|
–
|
–
|
|
|
25
|
|
$6.06M
|
+$1.62M
|
+64,394
|
+23%
|
|
