Comerica Bank’s Rhythm Pharmaceuticals RYTM Stock Holding History

Comerica Bank’s Portfolio RYTM Stock Details RYTM Fund Activity

Bought

Maintained

Sold

Quarter	Market Value	Status	Shares	Change in Stake	Trade Value	Portfolio Weight	Portfolio Position
2025 Q4	$430K	Sell	4,014 -205,311	-98%	-$21.8M	﹤0.01%	1930
2025 Q3	$21.1M	Sell	209,325 -92,336	-31%	-$8.57M	0.08%	247
2025 Q2	$19.1M	Buy	301,661 +56,907	+23%	+$3.48M	0.07%	267
2025 Q1	$13M	Buy	244,754 +227,641	+1,330%	+$12.6M	0.05%	332
2024 Q4	$958K	Sell	17,113 -447	-3%	-$24.7K	﹤0.01%	1565
2024 Q3	$920K	Sell	17,560 -2,839	-14%	-$136K	﹤0.01%	1594
2024 Q2	$838K	Sell	20,399 -12,719	-38%	-$508K	﹤0.01%	1586
2024 Q1	$1.44M	Sell	33,118 -933	-3%	-$40.8K	0.01%	1338
2023 Q4	$1.57M	Sell	34,051 -11,620	-25%	-$367K	0.01%	1299
2023 Q3	$1.05M	Buy	+45,671	New	+$1.02M	0.01%	1421

Other funds holding RYTM

RCM

RA Capital Management Boston, Massachusetts $9.44B AUM 157.3% 1-Year Est. Return

BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return

Vanguard Group Malvern, Pennsylvania $6.9T AUM 27.45% 1-Year Est. Return

BBA

Baker Bros. Advisors New York $17.4B AUM 131.5% 1-Year Est. Return

Primecap Management Pasadena, California $127B AUM 44.11% 1-Year Est. Return

NMC

NEA Management Company Timonium, Maryland $1.76B AUM 223.33% 1-Year Est. Return

Perceptive Advisors New York $5.12B AUM 314.02% 1-Year Est. Return

State Street Boston, Massachusetts $2.9T AUM 29.55% 1-Year Est. Return

Goldman Sachs New York $871B AUM 31.28% 1-Year Est. Return

Fidelity Investments Boston, Massachusetts $1.9T AUM 41.92% 1-Year Est. Return

Comerica Bank's RYTM Position: Q4 2025 in Review

Comerica Bank reduced its Rhythm Pharmaceuticals (RYTM) stake by 98% in Q4 2025, selling an estimated $21.8M and leaving 4,014 shares worth $430K. The position accounts for ﹤0.01% of the portfolio, ranked #1930.

Comerica Bank first reported a position in RYTM in Q3 2023 and has held it in 10 quarters since. The position peaked at $21.1M in Q3 2025. 279 funds tracked by Wall St. Rank hold RYTM as of Q4 2025.

Comerica Bank held 4,014 shares of Rhythm Pharmaceuticals worth $430K as of Q4 2025.
Comerica Bank sold 205,311 Rhythm Pharmaceuticals shares in Q4 2025, an estimated $21.8M.
Rhythm Pharmaceuticals made up ﹤0.01% of Comerica Bank's portfolio in Q4 2025, its #1930 holding.
Comerica Bank first reported a position in Rhythm Pharmaceuticals in Q3 2023 and has held it in 10 quarters since.
Comerica Bank's Rhythm Pharmaceuticals position peaked at $21.1M in Q3 2025.
279 funds tracked by Wall St. Rank held Rhythm Pharmaceuticals as of Q4 2025.

Based on Comerica Bank's 13F filing for Q4 2025, filed 29 Jan 2026.