Sofinnova Investments’s Rhythm Pharmaceuticals RYTM Stock Holding History

Sofinnova Investments’s Portfolio RYTM Stock Details RYTM Fund Activity

Bought

Maintained

Sold

Quarter	Market Value	Status	Shares	Change in Stake	Trade Value	Portfolio Weight	Portfolio Position
2026 Q2	$45.3M	Sell	408,027 -42,069	-9%	-$3.8M	2.34%	12
2026 Q1	$39.1M	Buy	450,096 +178,702	+66%	+$17.4M	1.49%	22
2025 Q4	$29.1M	Buy	271,394 +24,428	+10%	+$2.59M	1.25%	28
2025 Q3	$24.9M	Sell	246,966 -339,044	-58%	-$31.5M	1.36%	25
2025 Q2	$37M	Buy	586,010 +139,171	+31%	+$8.52M	2.26%	14
2025 Q1	$23.7M	Buy	446,839 +49,411	+12%	+$2.74M	1.55%	20
2024 Q4	$22.2M	Buy	397,428 +120,750	+44%	+$6.67M	1.62%	21
2024 Q3	$14.5M	Buy	+276,678	New	+$13.3M	1.15%	23
2020 Q1	–	Sell	-21,319	Closed	-$489K	–	69
2019 Q4	$489K	Buy	+21,319	New	+$474K	0.04%	58
2018 Q4	–	Sell	-159,302	Closed	-$4.65M	–	69
2018 Q3	$4.65M	Buy	159,302 +19,002	+14%	+$600K	0.41%	40
2018 Q2	$4.39M	Buy	+140,300	New	+$3.84M	0.5%	36

Other funds holding RYTM

RCM

RA Capital Management Boston, Massachusetts $11.5B AUM 168.77% 1-Year Est. Return

BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return

BBA

Baker Bros. Advisors New York $20B AUM 154.41% 1-Year Est. Return

Primecap Management Pasadena, California $169B AUM 114.72% 1-Year Est. Return

Vanguard Portfolio Management Malvern, Pennsylvania $2.22T AUM

Vanguard Capital Management Malvern, Pennsylvania $4.68T AUM

JP Morgan Chase New York $1.81T AUM 41.13% 1-Year Est. Return

Perceptive Advisors New York $6.66B AUM 360.84% 1-Year Est. Return

State Street Boston, Massachusetts $3.37T AUM 44.26% 1-Year Est. Return

T. Rowe Price Associates Baltimore, Maryland $999B AUM 46.22% 1-Year Est. Return

Sofinnova Investments's RYTM Position: Q2 2026 in Review

Sofinnova Investments reduced its Rhythm Pharmaceuticals (RYTM) stake by 9.3% in Q2 2026, selling an estimated $3.8M and leaving 408,027 shares worth $45.3M. The position accounts for 2.34% of the portfolio, ranked #12.

Sofinnova Investments first reported a position in RYTM in Q2 2018 and has held it in 11 quarters since. 304 funds tracked by Wall St. Rank hold RYTM as of Q2 2026.

Sofinnova Investments held 408,027 shares of Rhythm Pharmaceuticals worth $45.3M as of Q2 2026.
Sofinnova Investments sold 42,069 Rhythm Pharmaceuticals shares in Q2 2026, an estimated $3.8M.
Rhythm Pharmaceuticals made up 2.34% of Sofinnova Investments's portfolio in Q2 2026, its #12 holding.
Sofinnova Investments first reported a position in Rhythm Pharmaceuticals in Q2 2018 and has held it in 11 quarters since.
304 funds tracked by Wall St. Rank held Rhythm Pharmaceuticals as of Q2 2026.

Based on Sofinnova Investments's 13F filing for Q2 2026, filed 14 Aug 2026.