|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$1.11B
|
+$142M
|
+2,047,794
|
+14%
|
|
|
2
|
Vanguard Group
Malvern,
Pennsylvania
|
$665M
|
+$89M
|
+1,284,883
|
+15%
|
|
|
3
|
|
$650M
|
+$64.9M
|
+937,160
|
+11%
|
|
|
4
|
RA Capital Management
Boston,
Massachusetts
|
$560M
|
+$21.6M
|
+312,500
|
+4%
|
|
|
5
|
Janus Henderson Group
London,
|
$524M
|
+$48M
|
+692,492
|
+10%
|
|
|
6
|
Wellington Management Group
Boston,
Massachusetts
|
$336M
|
+$33.8M
|
+487,450
|
+11%
|
|
|
7
|
Capital Research Global Investors
Los Angeles,
California
|
$283M
|
+$48.5M
|
+700,414
|
+20%
|
|
|
8
|
T. Rowe Price Investment Management
Baltimore,
Maryland
|
$243M
|
+$160M
|
+2,306,926
|
+185%
|
|
|
9
|
State Street
Boston,
Massachusetts
|
$228M
|
-$3.63M
|
-52,436
|
-2%
|
|
|
10
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$217M
|
+$34.5M
|
+498,359
|
+19%
|
|
|
11
|
Darwin Global Management
St. Helier,
Jersey
|
$188M
|
+$150M
|
+2,170,845
|
+374%
|
|
|
12
|
Geode Capital Management
Boston,
Massachusetts
|
$156M
|
+$21.7M
|
+313,869
|
+16%
|
|
|
13
|
Franklin Resources
San Mateo,
California
|
$147M
|
+$74.1M
|
+1,070,736
|
+99%
|
|
|
14
|
Perceptive Advisors
New York
|
$132M
|
+$58.5M
|
+844,273
|
+78%
|
|
|
15
|
Driehaus Capital Management
Chicago,
Illinois
|
$128M
|
+$13.4M
|
+193,439
|
+12%
|
|
|
16
|
AllianceBernstein
Nashville,
Tennessee
|
$122M
|
-$9.3M
|
-134,344
|
-7%
|
|
|
17
|
Westfield Capital Management
Boston,
Massachusetts
|
$108M
|
+$9.04M
|
+130,502
|
+9%
|
|
|
18
|
Fred Alger Management
New York
|
$95.4M
|
-$18.9M
|
-273,478
|
-16%
|
|
|
19
|
Jennison Associates
New York
|
$85.9M
|
-$15.2M
|
-219,271
|
-15%
|
|
|
20
|
Paradigm Biocapital Advisors
New York
|
$84.7M
|
+$85.9M
|
+1,239,995
|
New
|
|
|
21
|
|
$84.3M
|
+$69.8M
|
+1,007,558
|
+444%
|
|
|
22
|
Braidwell
Stamford,
Connecticut
|
$82.8M
|
-$5.35M
|
-77,262
|
-6%
|
|
|
23
|
|
$79.4M
|
+$52.4M
|
+756,443
|
+187%
|
|
|
24
|
Frazier Life Sciences Management
Palo Alto,
California
|
$77.8M
|
-$1.73M
|
-25,000
|
-2%
|
|
|
25
|
|
$72.8M
|
-$6.02M
|
-86,960
|
-8%
|
|
