|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$202M
|
+$11M
|
+502,592
|
+6%
|
|
|
2
|
RA Capital Management
Boston,
Massachusetts
|
$111M
|
+$7.44M
|
+340,739
|
+8%
|
|
|
3
|
Janus Henderson Group
London,
|
$105M
|
+$1.82M
|
+83,100
|
+2%
|
|
|
4
|
Abingworth
London,
United Kingdom
|
$101M
|
–
|
–
|
–
|
|
|
5
|
TPG GP A
Fort Worth,
Texas
|
$97.9M
|
-$3.33M
|
-152,483
|
-4%
|
|
|
6
|
Vanguard Group
Malvern,
Pennsylvania
|
$87.6M
|
+$10.8M
|
+495,078
|
+16%
|
|
|
7
|
|
$69.7M
|
+$2.38M
|
+108,975
|
+4%
|
|
|
8
|
Frazier Life Sciences Management
Palo Alto,
California
|
$55.8M
|
+$50.5M
|
+2,309,554
|
New
|
|
|
9
|
Medicxi Ventures Management
St. Helier,
Jersey
|
$45.6M
|
–
|
–
|
–
|
|
|
10
|
|
$36.6M
|
+$9.11M
|
+416,959
|
+38%
|
|
|
11
|
State Street
Boston,
Massachusetts
|
$33.4M
|
+$4.57M
|
+209,237
|
+18%
|
|
|
12
|
EcoR1 Capital
San Francisco,
California
|
$31.5M
|
+$28.1M
|
+1,283,941
|
+6,173%
|
|
|
13
|
Wellington Management Group
Boston,
Massachusetts
|
$27.6M
|
-$179K
|
-8,210
|
-0.7%
|
|
|
14
|
Pivotal bioVenture Partners Investment Advisor
San Francisco,
California
|
$26.8M
|
–
|
–
|
–
|
|
|
15
|
Great Point Partners
Greenwich,
Connecticut
|
$21.4M
|
+$8.41M
|
+385,153
|
+77%
|
|
|
16
|
Geode Capital Management
Boston,
Massachusetts
|
$17.4M
|
+$1.45M
|
+66,246
|
+10%
|
|
|
17
|
Citadel Advisors
Miami,
Florida
|
$17.3M
|
+$13.9M
|
+635,105
|
+767%
|
|
|
18
|
Kynam Capital Management
Princeton,
New Jersey
|
$14M
|
+$8.04M
|
+368,157
|
+174%
|
|
|
19
|
Northern Trust
Chicago,
Illinois
|
$9.23M
|
+$233K
|
+10,663
|
+3%
|
|
|
20
|
|
$8.27M
|
+$3.15M
|
+144,074
|
+73%
|
|
|
21
|
Soleus Capital Management
Greenwich,
Connecticut
|
$7.93M
|
+$734K
|
+33,600
|
+11%
|
|
|
22
|
Ikarian Capital
Dallas,
Texas
|
$7.63M
|
+$456K
|
+20,880
|
+7%
|
|
|
23
|
Ghost Tree Capital
New York
|
$7.25M
|
+$1.09M
|
+50,000
|
+20%
|
|
|
24
|
Millennium Management
New York
|
$6.34M
|
-$516K
|
-23,603
|
-8%
|
|
|
25
|
Charles Schwab
San Francisco,
California
|
$6.33M
|
+$436K
|
+19,972
|
+8%
|
|
