|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$702M
|
+$107M
|
+2,247,671
|
+19%
|
|
|
2
|
Vanguard Group
Malvern,
Pennsylvania
|
$411M
|
+$80.8M
|
+1,704,058
|
+26%
|
|
|
3
|
RA Capital Management
Boston,
Massachusetts
|
$394M
|
+$28.4M
|
+600,000
|
+8%
|
|
|
4
|
|
$353M
|
+$94M
|
+1,983,223
|
+39%
|
|
|
5
|
Janus Henderson Group
London,
|
$353M
|
-$3.22M
|
-67,860
|
-1%
|
|
|
6
|
Wellington Management Group
Boston,
Massachusetts
|
$221M
|
+$56.5M
|
+1,191,937
|
+37%
|
|
|
7
|
Capital Research Global Investors
Los Angeles,
California
|
$168M
|
+$24.2M
|
+511,121
|
+18%
|
|
|
8
|
State Street
Boston,
Massachusetts
|
$158M
|
+$4.14M
|
+87,296
|
+3%
|
|
|
9
|
Fred Alger Management
New York
|
$118M
|
+$72.4M
|
+1,526,440
|
+181%
|
|
|
10
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$109M
|
+$102M
|
+2,160,354
|
+6,745%
|
|
|
11
|
AllianceBernstein
Nashville,
Tennessee
|
$94.3M
|
+$85.5M
|
+1,804,718
|
+2,164%
|
|
|
12
|
Braidwell
Stamford,
Connecticut
|
$86M
|
+$19.1M
|
+402,375
|
+30%
|
|
|
13
|
Geode Capital Management
Boston,
Massachusetts
|
$84.2M
|
+$16.9M
|
+355,875
|
+27%
|
|
|
14
|
Perceptive Advisors
New York
|
$80.6M
|
+$21.1M
|
+444,122
|
+38%
|
|
|
15
|
Pictet Asset Management (Switzerland)
Geneva 73,
Switzerland
|
$73.9M
|
+$38.4M
|
+810,663
|
+121%
|
|
|
16
|
Jennison Associates
New York
|
$72.6M
|
+$1.16M
|
+24,463
|
+2%
|
|
|
17
|
Medicxi Ventures Management
St. Helier,
Jersey
|
$65.7M
|
-$6.72M
|
-141,865
|
-10%
|
|
|
18
|
Kynam Capital Management
Princeton,
New Jersey
|
$64.9M
|
+$3.94M
|
+83,216
|
+7%
|
|
|
19
|
Millennium Management
New York
|
$60.6M
|
-$4.72M
|
-99,570
|
-8%
|
|
|
20
|
Driehaus Capital Management
Chicago,
Illinois
|
$59.4M
|
+$27.3M
|
+575,951
|
+94%
|
|
|
21
|
Frazier Life Sciences Management
Palo Alto,
California
|
$58.2M
|
-$11M
|
-233,000
|
-17%
|
|
|
22
|
T. Rowe Price Investment Management
Baltimore,
Maryland
|
$57.1M
|
+$19.4M
|
+409,011
|
+56%
|
|
|
23
|
Commodore Capital
New York
|
$50.7M
|
+$38.6M
|
+815,000
|
+408%
|
|
|
24
|
|
$50.3M
|
+$13.2M
|
+277,709
|
+38%
|
|
|
25
|
Avidity Partners Management
Dallas,
Texas
|
$43.7M
|
+$17.3M
|
+365,000
|
+72%
|
|
