|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$152M
|
+$1.43M
|
+56,738
|
+0.7%
|
|
|
2
|
TPG Group Holdings (SBS) Advisors
Fort Worth,
Texas
|
$90M
|
-$9.63M
|
-382,738
|
-8%
|
|
|
3
|
Janus Henderson Group
London,
|
$83.5M
|
+$844K
|
+33,529
|
+0.8%
|
|
|
4
|
Abingworth
London,
United Kingdom
|
$82.1M
|
–
|
–
|
–
|
|
|
5
|
RA Capital Management
Boston,
Massachusetts
|
$76.3M
|
+$3.9M
|
+155,109
|
+4%
|
|
|
6
|
Vanguard Group
Malvern,
Pennsylvania
|
$54.7M
|
+$33.3M
|
+1,321,937
|
+91%
|
|
|
7
|
Frazier Management
Seattle,
Washington
|
$45.6M
|
–
|
–
|
–
|
|
|
8
|
|
$43.2M
|
+$12.5M
|
+495,700
|
+29%
|
|
|
9
|
Medicxi Ventures Management
St. Helier,
Jersey
|
$37.3M
|
–
|
–
|
–
|
|
|
10
|
State Street
Boston,
Massachusetts
|
$35M
|
+$21.4M
|
+850,246
|
+92%
|
|
|
11
|
Pivotal bioVenture Partners Investment Advisor
San Francisco,
California
|
$27.8M
|
-$20.6M
|
-817,549
|
-37%
|
|
|
12
|
Wellington Management Group
Boston,
Massachusetts
|
$19.7M
|
-$313K
|
-12,440
|
-1%
|
|
|
13
|
Perceptive Advisors
New York
|
$16.8M
|
–
|
–
|
–
|
|
|
14
|
|
$12.8M
|
+$466K
|
+18,514
|
+3%
|
|
|
15
|
Ikarian Capital
Dallas,
Texas
|
$9.9M
|
+$5.66M
|
+225,000
|
+81%
|
|
|
16
|
Geode Capital Management
Boston,
Massachusetts
|
$8.31M
|
+$3.03M
|
+120,311
|
+40%
|
|
|
17
|
Novo Holdings A/S
Hellerup,
Denmark
|
$8.23M
|
–
|
–
|
–
|
|
|
18
|
Opaleye Management
Boston,
Massachusetts
|
$7.07M
|
+$569K
|
+22,600
|
+7%
|
|
|
19
|
Millennium Management
New York
|
$6.98M
|
-$1.82M
|
-72,370
|
-17%
|
|
|
20
|
Soleus Capital Management
Greenwich,
Connecticut
|
$5.8M
|
+$7.39M
|
+293,650
|
New
|
|
|
21
|
Northern Trust
Chicago,
Illinois
|
$5.75M
|
+$1.71M
|
+67,838
|
+30%
|
|
|
22
|
|
$3.58M
|
-$2.89M
|
-114,808
|
-39%
|
|
|
23
|
Sabby Management
Miami Beach,
Florida
|
$3.54M
|
+$4.5M
|
+178,992
|
New
|
|
|
24
|
Charles Schwab
San Francisco,
California
|
$2.69M
|
+$468K
|
+18,585
|
+16%
|
|
|
25
|
UBS Group
Zurich,
Switzerland
|
$2.28M
|
+$1.19M
|
+47,284
|
+69%
|
|
