|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$185M
|
+$3.16M
|
+136,464
|
+2%
|
|
|
2
|
RA Capital Management
Boston,
Massachusetts
|
$99.7M
|
–
|
–
|
–
|
|
|
3
|
Janus Henderson Group
London,
|
$91.9M
|
-$2.44M
|
-105,277
|
-2%
|
|
|
4
|
Abingworth
London,
United Kingdom
|
$90.7M
|
–
|
–
|
–
|
|
|
5
|
Vanguard Group
Malvern,
Pennsylvania
|
$86.1M
|
+$7.56M
|
+326,554
|
+9%
|
|
|
6
|
TPG GP A
Fort Worth,
Texas
|
$79.8M
|
-$8.97M
|
-387,667
|
-10%
|
|
|
7
|
|
$71.2M
|
+$8.92M
|
+385,608
|
+13%
|
|
|
8
|
Medicxi Ventures Management
St. Helier,
Jersey
|
$41.1M
|
–
|
–
|
–
|
|
|
9
|
State Street
Boston,
Massachusetts
|
$40.4M
|
+$10.9M
|
+471,476
|
+34%
|
|
|
10
|
Frazier Life Sciences Management
Palo Alto,
California
|
$38.9M
|
-$12.1M
|
-522,149
|
-23%
|
|
|
11
|
Citadel Advisors
Miami,
Florida
|
$21.8M
|
+$6.6M
|
+285,031
|
+40%
|
|
|
12
|
Great Point Partners
Greenwich,
Connecticut
|
$21.4M
|
+$2.31M
|
+100,000
|
+11%
|
|
|
13
|
Pivotal bioVenture Partners Investment Advisor
San Francisco,
California
|
$18.1M
|
-$6.46M
|
-279,319
|
-25%
|
|
|
14
|
Novo Holdings A/S
Hellerup,
Denmark
|
$17.9M
|
+$19.1M
|
+823,705
|
New
|
|
|
15
|
Geode Capital Management
Boston,
Massachusetts
|
$17M
|
+$1.34M
|
+57,732
|
+8%
|
|
|
16
|
Kynam Capital Management
Princeton,
New Jersey
|
$15.7M
|
+$3.34M
|
+144,141
|
+25%
|
|
|
17
|
Millennium Management
New York
|
$12.3M
|
+$7.02M
|
+303,396
|
+115%
|
|
|
18
|
Driehaus Capital Management
Chicago,
Illinois
|
$11.9M
|
+$10.6M
|
+458,190
|
+509%
|
|
|
19
|
Woodline Partners
San Francisco,
California
|
$10.1M
|
+$10.8M
|
+466,324
|
New
|
|
|
20
|
Northern Trust
Chicago,
Illinois
|
$10.1M
|
+$1.9M
|
+82,212
|
+22%
|
|
|
21
|
Soleus Capital Management
Greenwich,
Connecticut
|
$8.06M
|
+$979K
|
+42,300
|
+13%
|
|
|
22
|
Polar Asset Management Partners
Toronto,
Ontario, Canada
|
$7.74M
|
+$8.23M
|
+355,700
|
New
|
|
|
23
|
|
$7.69M
|
+$251K
|
+10,830
|
+3%
|
|
|
24
|
Ghost Tree Capital
New York
|
$7.07M
|
+$579K
|
+25,000
|
+8%
|
|
|
25
|
Charles Schwab
San Francisco,
California
|
$6.3M
|
+$633K
|
+27,356
|
+10%
|
|
