Group One Trading
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Group One Trading’s Spero Therapeutics SPRO Stock Holding History

Group One Trading’s Portfolio SPRO Stock Details SPRO Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$43.1K Sell
18,400
-93,400
-84% -$222K ﹤0.01% 5375
2025
Q4 		$260K Buy
111,800
+23,300
+26% +$54.1K ﹤0.01% 4131
2025
Q3 		$166K Sell
88,500
-22,900
-21% -$50.4K ﹤0.01% 4873
2025
Q2 		$323K Buy
+111,400
New +$160K ﹤0.01% 3847
2024
Q3 		– Sell
-6,500
Closed -$8.45K – 7329
2024
Q2 		$8.45K Hold
6,500
– – ﹤0.01% 5717
2024
Q1 		$11.2K Buy
+6,500
New +$10.2K ﹤0.01% 5812
2023
Q3 		– Sell
-17,000
Closed -$24.6K – 8253
2023
Q2 		$24.6K Buy
17,000
+10,400
+158% +$17.8K ﹤0.01% 5831
2023
Q1 		$9.57K Sell
6,600
-83,200
-93% -$139K ﹤0.01% 5959
2022
Q4 		$155K Buy
89,800
+48,100
+115% +$89.8K ﹤0.01% 4071
2022
Q3 		$83K Buy
41,700
+34,900
+513% +$34.7K ﹤0.01% 4946
2022
Q2 		$5K Buy
6,800
+1,800
+36% +$5.23K ﹤0.01% 7127
2022
Q1 		$44K Buy
5,000
+4,800
+2,400% +$49.2K ﹤0.01% 6189
2021
Q4 		$3K Sell
200
-29,900
-99% -$475K ﹤0.01% 7811
2021
Q3 		$554K Buy
30,100
+8,500
+39% +$136K ﹤0.01% 4070
2021
Q2 		$302K Buy
21,600
+14,700
+213% +$205K ﹤0.01% 4781
2021
Q1 		$102K Buy
6,900
+6,700
+3,350% +$118K ﹤0.01% 5643
2020
Q4 		$4K Sell
200
-800
-80% -$12.5K ﹤0.01% 6112
2020
Q3 		$11K Hold
1,000
– – ﹤0.01% 5389
2020
Q2 		$14K Buy
+1,000
New +$11.2K ﹤0.01% 5001

Other funds holding SPRO

GP
GSK plc London $599M AUM
P
Pfizer New York $239M AUM 232.47% 1-Year Est. Return
VCM
Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM
Renaissance Technologies
Renaissance Technologies New York $63.9B AUM 45.56% 1-Year Est. Return
AI
Alphabet Inc Mountain View, California $4.02B AUM 215.74% 1-Year Est. Return
Two Sigma Investments
Two Sigma Investments New York $124B AUM 33.93% 1-Year Est. Return
AFM
Anson Funds Management Dallas, Texas $2.29B AUM 370.24% 1-Year Est. Return
Geode Capital Management
Geode Capital Management Boston, Massachusetts $1.61T AUM 30.72% 1-Year Est. Return
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
Citadel Advisors
Citadel Advisors Miami, Florida $618B AUM 30.34% 1-Year Est. Return

Group One Trading's SPRO Position: Q4 2025 in Review

Group One Trading sold out of Spero Therapeutics (SPRO) in Q4 2025, closing a stake of 16,879 shares — an estimated $39.2K sold.

Group One Trading first reported a position in SPRO in Q4 2018 and held it in 15 quarters. The position peaked at $133K in Q2 2023. 56 funds tracked by Wall St. Rank hold SPRO as of Q4 2025.

  • Group One Trading reported no remaining Spero Therapeutics position as of Q4 2025 after selling out during the quarter.
  • Group One Trading sold 16,879 Spero Therapeutics shares in Q4 2025, an estimated $39.2K.
  • Group One Trading first reported a position in Spero Therapeutics in Q4 2018 and held it in 15 quarters.
  • Group One Trading's Spero Therapeutics position peaked at $133K in Q2 2023.
  • 56 funds tracked by Wall St. Rank held Spero Therapeutics as of Q4 2025.

Based on Group One Trading's 13F filing for Q4 2025, filed 12 Feb 2026.