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UPB

Upstream Bio Inc

Name Holding Trade Value Shares
Change
Change in
Stake
SFM
26
Sphera Funds Management
Israel
$3.22M +$6.44M +358,000 New
PBM
27
Propel Bio Management
California
$3.1M +$6.15M +341,779 New
Wellington Management Group
28
Wellington Management Group
Massachusetts
$3.08M -$9.94M -552,380 -62%
JF
29
Jump Financial
Illinois
$2.87M +$5.75M +319,400 New
Goldman Sachs
30
Goldman Sachs
New York
$2.85M -$304K -16,894 -5%
Alyeska Investment Group
31
Alyeska Investment Group
Illinois
$2.68M
Northern Trust
32
Northern Trust
Illinois
$2.35M +$435K +24,193 +10%
Charles Schwab
33
Charles Schwab
California
$2.32M -$489K -27,202 -10%
PM
34
Prosight Management
Texas
$2.17M +$4.34M +241,123 New
UBS Group
35
UBS Group
Switzerland
$2.08M -$28.3M -1,574,989 -87%
Vanguard Fiduciary Trust
36
Vanguard Fiduciary Trust
Pennsylvania
$2.02M +$4.03M +224,157 New
XT
37
XTX Topco
Cayman Islands
$1.88M +$3.49M +194,186 +1,287%
Arrowstreet Capital
38
Arrowstreet Capital
Massachusetts
$1.67M +$3.33M +185,087 New
TCM
39
TCG Crossover Management
California
$1.63M -$10.1M -562,823 -76%
Deutsche Bank
40
Deutsche Bank
Germany
$1.63M +$955K +53,074 +42%
Point72 Asset Management
41
Point72 Asset Management
Connecticut
$1.6M +$3.21M +178,168 New
TI
42
Trexquant Investment
Connecticut
$1.59M +$2.62M +145,608 +469%
SSA
43
Schonfeld Strategic Advisors
New York
$1.45M +$819K +45,542 +39%
BCM
44
Boxer Capital Management
California
$1.35M
BNP Paribas Financial Markets
45
BNP Paribas Financial Markets
France
$1.13M +$2.18M +121,024 +2,432%
AllianceBernstein
46
AllianceBernstein
Tennessee
$842K
ECM
47
ExodusPoint Capital Management
New York
$823K +$288K +16,029 +21%
American Century Companies
48
American Century Companies
Missouri
$789K -$2.38K -132 -0.2%
Bank of New York Mellon
49
Bank of New York Mellon
New York
$732K -$62.4K -3,470 -4%
Dimensional Fund Advisors
50
Dimensional Fund Advisors
Texas
$719K +$1.44M +80,002 New