ECM
UPB

ExodusPoint Capital Management’s Upstream Bio Inc UPB Stock Holding History

ExodusPoint Capital Management’s Portfolio UPB Stock Details UPB Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$823K Buy
91,431
+16,029
+21% +$288K 0.01% 1046
2025
Q4 		$2.05M Buy
+75,402
New +$1.88M 0.02% 755

Other funds holding UPB

Fidelity Investments
Fidelity Investments Boston, Massachusetts $1.9T AUM 41.92% 1-Year Est. Return
O
OrbiMed New York $5.05B AUM 125.28% 1-Year Est. Return
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
DC
Decheng Capital Menlo Park, California $661M AUM 299.97% 1-Year Est. Return
ES
Enavate Sciences Menlo Park, California $352M AUM 220.14% 1-Year Est. Return
VCM
Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM
YIH
Y-Intercept (HK) Hong Kong $5.05B AUM 17.89% 1-Year Est. Return
Federated Hermes
Federated Hermes Pittsburgh, Pennsylvania $61.5B AUM 30.7% 1-Year Est. Return
Geode Capital Management
Geode Capital Management Boston, Massachusetts $1.61T AUM 30.72% 1-Year Est. Return
Millennium Management
Millennium Management New York $240B AUM 35.51% 1-Year Est. Return

ExodusPoint Capital Management's UPB Position: Q1 2026 in Review

ExodusPoint Capital Management increased its Upstream Bio Inc (UPB) stake by 21% in Q1 2026, buying an estimated $288K and bringing the position to 91,431 shares worth $823K. The position accounts for 0.01% of the portfolio, ranked #1046.

ExodusPoint Capital Management first reported a position in UPB in Q4 2025 and has held it in 2 quarters since. The position peaked at $2.05M in Q4 2025. 140 funds tracked by Wall St. Rank hold UPB as of Q1 2026.

  • ExodusPoint Capital Management held 91,431 shares of Upstream Bio Inc worth $823K as of Q1 2026.
  • ExodusPoint Capital Management bought 16,029 Upstream Bio Inc shares in Q1 2026, an estimated $288K.
  • Upstream Bio Inc made up 0.01% of ExodusPoint Capital Management's portfolio in Q1 2026, its #1046 holding.
  • ExodusPoint Capital Management first reported a position in Upstream Bio Inc in Q4 2025 and has held it in 2 quarters since.
  • ExodusPoint Capital Management's Upstream Bio Inc position peaked at $2.05M in Q4 2025.
  • 140 funds tracked by Wall St. Rank held Upstream Bio Inc as of Q1 2026.

Based on ExodusPoint Capital Management's 13F filing for Q1 2026, filed 14 May 2026.