BlackRock
UPB

BlackRock’s Upstream Bio Inc UPB Stock Holding History

BlackRock’s Portfolio UPB Stock Details UPB Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$30.3M Buy
3,370,689
+26,185
+0.8% +$471K ﹤0.01% 2816
2025
Q4 		$90.8M Buy
3,344,504
+740,798
+28% +$18.4M ﹤0.01% 2162
2025
Q3 		$49M Buy
2,603,706
+507,200
+24% +$7.88M ﹤0.01% 2512
2025
Q2 		$23M Buy
2,096,506
+910,738
+77% +$8.41M ﹤0.01% 2936
2025
Q1 		$7.26M Buy
1,185,768
+67,968
+6% +$649K ﹤0.01% 3478
2024
Q4 		$18.4M Buy
+1,117,800
New +$25M ﹤0.01% 3102

Other funds holding UPB

Fidelity Investments
Fidelity Investments Boston, Massachusetts $1.9T AUM 41.92% 1-Year Est. Return
O
OrbiMed New York $4.59B AUM 125.28% 1-Year Est. Return
DC
Decheng Capital Menlo Park, California $661M AUM 299.97% 1-Year Est. Return
ES
Enavate Sciences Menlo Park, California $352M AUM 220.14% 1-Year Est. Return
VCM
Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM
YIH
Y-Intercept (HK) Hong Kong $5.05B AUM 17.89% 1-Year Est. Return
Federated Hermes
Federated Hermes Pittsburgh, Pennsylvania $61.5B AUM 30.7% 1-Year Est. Return
Geode Capital Management
Geode Capital Management Boston, Massachusetts $1.61T AUM 30.72% 1-Year Est. Return
Millennium Management
Millennium Management New York $134B AUM 35.51% 1-Year Est. Return
SAM
SEB Asset Management Stockholm $23.4B AUM