JP Morgan Chase
UPB

JP Morgan Chase’s Upstream Bio Inc UPB Stock Holding History

JP Morgan Chase’s Portfolio UPB Stock Details UPB Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q2 		$7.01M Buy
1,012,044
+549,043
+119% +$4.6M ﹤0.01% 3129
2026
Q1 		$4.07M Buy
463,001
+352,721
+320% +$6.35M ﹤0.01% 3511
2025
Q4 		$2.99M Buy
110,280
+80,333
+268% +$2M ﹤0.01% 3766
2025
Q3 		$563K Buy
29,947
+13,478
+82% +$209K ﹤0.01% 4949
2025
Q2 		$181K Buy
16,469
+1,275
+8% +$11.8K ﹤0.01% 5289
2025
Q1 		$93K Sell
15,194
-32,598
-68% -$311K ﹤0.01% 5603
2024
Q4 		$786K Buy
+47,792
New +$1.07M ﹤0.01% 4786

Other funds holding UPB

Fidelity Investments
Fidelity Investments Boston, Massachusetts $2.3T AUM 54.33% 1-Year Est. Return
O
OrbiMed New York $5.4B AUM 163.13% 1-Year Est. Return
Norges Bank
Norges Bank Oslo, Norway $1T AUM
BlackRock
BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return
DC
Decheng Capital Menlo Park, California $732M AUM 275.56% 1-Year Est. Return
ES
Enavate Sciences Menlo Park, California $345M AUM 134.64% 1-Year Est. Return
Vanguard Capital Management
Vanguard Capital Management Malvern, Pennsylvania $4.68T AUM
Millennium Management
Millennium Management New York $276B AUM 44.8% 1-Year Est. Return
D.E. Shaw & Co
D.E. Shaw & Co New York $210B AUM 57.28% 1-Year Est. Return
Qube Research & Technologies (QRT)
Qube Research & Technologies (QRT) London, United Kingdom $108B AUM 37.29% 1-Year Est. Return

JP Morgan Chase's UPB Position: Q2 2026 in Review

JP Morgan Chase increased its Upstream Bio Inc (UPB) stake by 119% in Q2 2026, buying an estimated $4.6M and bringing the position to 1,012,044 shares worth $7.01M. The position accounts for ﹤0.01% of the portfolio, ranked #3129.

JP Morgan Chase first reported a position in UPB in Q4 2024 and has held it in 7 quarters since. 149 funds tracked by Wall St. Rank hold UPB as of Q2 2026.

  • JP Morgan Chase held 1,012,044 shares of Upstream Bio Inc worth $7.01M as of Q2 2026.
  • JP Morgan Chase bought 549,043 Upstream Bio Inc shares in Q2 2026, an estimated $4.6M.
  • Upstream Bio Inc made up ﹤0.01% of JP Morgan Chase's portfolio in Q2 2026, its #3129 holding.
  • JP Morgan Chase first reported a position in Upstream Bio Inc in Q4 2024 and has held it in 7 quarters since.
  • 149 funds tracked by Wall St. Rank held Upstream Bio Inc as of Q2 2026.

Based on JP Morgan Chase's 13F filing for Q2 2026, filed 12 Aug 2026.