JP Morgan Chase
UPB

JP Morgan Chase’s Upstream Bio Inc UPB Stock Holding History

JP Morgan Chase’s Portfolio UPB Stock Details UPB Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$4.07M Buy
463,001
+352,721
+320% +$6.35M ﹤0.01% 3511
2025
Q4 		$2.99M Buy
110,280
+80,333
+268% +$2M ﹤0.01% 3766
2025
Q3 		$563K Buy
29,947
+13,478
+82% +$209K ﹤0.01% 4949
2025
Q2 		$181K Buy
16,469
+1,275
+8% +$11.8K ﹤0.01% 5289
2025
Q1 		$93K Sell
15,194
-32,598
-68% -$311K ﹤0.01% 5603
2024
Q4 		$786K Buy
+47,792
New +$1.07M ﹤0.01% 4786

Other funds holding UPB

Fidelity Investments
Fidelity Investments Boston, Massachusetts $1.9T AUM 41.92% 1-Year Est. Return
O
OrbiMed New York $5.05B AUM 125.28% 1-Year Est. Return
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
DC
Decheng Capital Menlo Park, California $661M AUM 299.97% 1-Year Est. Return
ES
Enavate Sciences Menlo Park, California $352M AUM 220.14% 1-Year Est. Return
VCM
Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM
YIH
Y-Intercept (HK) Hong Kong $5.05B AUM 17.89% 1-Year Est. Return
Federated Hermes
Federated Hermes Pittsburgh, Pennsylvania $61.5B AUM 30.7% 1-Year Est. Return
Geode Capital Management
Geode Capital Management Boston, Massachusetts $1.61T AUM 30.72% 1-Year Est. Return
Millennium Management
Millennium Management New York $240B AUM 35.51% 1-Year Est. Return

JP Morgan Chase's UPB Position: Q1 2026 in Review

JP Morgan Chase increased its Upstream Bio Inc (UPB) stake by 320% in Q1 2026, buying an estimated $6.35M and bringing the position to 463,001 shares worth $4.07M. The position accounts for ﹤0.01% of the portfolio, ranked #3511.

JP Morgan Chase first reported a position in UPB in Q4 2024 and has held it in 6 quarters since. 140 funds tracked by Wall St. Rank hold UPB as of Q1 2026.

  • JP Morgan Chase held 463,001 shares of Upstream Bio Inc worth $4.07M as of Q1 2026.
  • JP Morgan Chase bought 352,721 Upstream Bio Inc shares in Q1 2026, an estimated $6.35M.
  • Upstream Bio Inc made up ﹤0.01% of JP Morgan Chase's portfolio in Q1 2026, its #3511 holding.
  • JP Morgan Chase first reported a position in Upstream Bio Inc in Q4 2024 and has held it in 6 quarters since.
  • 140 funds tracked by Wall St. Rank held Upstream Bio Inc as of Q1 2026.

Based on JP Morgan Chase's 13F filing for Q1 2026, filed 13 May 2026.