Geode Capital Management
UPB

Geode Capital Management’s Upstream Bio Inc UPB Stock Holding History

Geode Capital Management’s Portfolio UPB Stock Details UPB Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q2 		$6.45M Sell
931,261
-19,356
-2% -$162K ﹤0.01% 2775
2026
Q1 		$8.56M Buy
950,617
+98,709
+12% +$1.78M ﹤0.01% 2466
2025
Q4 		$23.1M Buy
851,908
+34,799
+4% +$866K ﹤0.01% 1923
2025
Q3 		$15.4M Buy
817,109
+170,474
+26% +$2.65M ﹤0.01% 2152
2025
Q2 		$7.1M Buy
646,635
+235,958
+57% +$2.18M ﹤0.01% 2552
2025
Q1 		$2.51M Buy
410,677
+47,408
+13% +$453K ﹤0.01% 2955
2024
Q4 		$5.97M Buy
+363,269
New +$8.11M ﹤0.01% 2658

Other funds holding UPB

Fidelity Investments
Fidelity Investments Boston, Massachusetts $2.3T AUM 54.33% 1-Year Est. Return
O
OrbiMed New York $5.4B AUM 163.13% 1-Year Est. Return
Norges Bank
Norges Bank Oslo, Norway $1T AUM
BlackRock
BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return
DC
Decheng Capital Menlo Park, California $732M AUM 275.56% 1-Year Est. Return
ES
Enavate Sciences Menlo Park, California $345M AUM 134.64% 1-Year Est. Return
Vanguard Capital Management
Vanguard Capital Management Malvern, Pennsylvania $4.68T AUM
Millennium Management
Millennium Management New York $276B AUM 44.8% 1-Year Est. Return
D.E. Shaw & Co
D.E. Shaw & Co New York $210B AUM 57.28% 1-Year Est. Return
JP Morgan Chase
JP Morgan Chase New York $1.81T AUM 41.13% 1-Year Est. Return

Geode Capital Management's UPB Position: Q2 2026 in Review

Geode Capital Management reduced its Upstream Bio Inc (UPB) stake by 2% in Q2 2026, selling an estimated $162K and leaving 931,261 shares worth $6.45M. The position accounts for ﹤0.01% of the portfolio, ranked #2775.

Geode Capital Management first reported a position in UPB in Q4 2024 and has held it in 7 quarters since. The position peaked at $23.1M in Q4 2025. 149 funds tracked by Wall St. Rank hold UPB as of Q2 2026.

  • Geode Capital Management held 931,261 shares of Upstream Bio Inc worth $6.45M as of Q2 2026.
  • Geode Capital Management sold 19,356 Upstream Bio Inc shares in Q2 2026, an estimated $162K.
  • Upstream Bio Inc made up ﹤0.01% of Geode Capital Management's portfolio in Q2 2026, its #2775 holding.
  • Geode Capital Management first reported a position in Upstream Bio Inc in Q4 2024 and has held it in 7 quarters since.
  • Geode Capital Management's Upstream Bio Inc position peaked at $23.1M in Q4 2025.
  • 149 funds tracked by Wall St. Rank held Upstream Bio Inc as of Q2 2026.

Based on Geode Capital Management's 13F filing for Q2 2026, filed 12 Aug 2026.