Geode Capital Management’s Upstream Bio, Inc. Common Stock UPB Stock Holding History

Bought

Maintained

Sold

Quarter	Market Value	Status	Shares	Shares Change %	Capital Flow	Portfolio Weight	Portfolio Position
2025 Q2	$7.1M	Buy	646,635 +235,958	+57%	+$2.59M	﹤0.01%	2552
2025 Q1	$2.51M	Buy	410,677 +47,408	+13%	+$290K	﹤0.01%	2955
2024 Q4	$5.97M	Buy	+363,269	New	+$5.97M	﹤0.01%	2658