Geode Capital Management
UPB

Geode Capital Management’s Upstream Bio Inc UPB Stock Holding History

Geode Capital Management’s Portfolio UPB Stock Details UPB Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$8.56M Buy
950,617
+98,709
+12% +$1.78M ﹤0.01% 2466
2025
Q4 		$23.1M Buy
851,908
+34,799
+4% +$866K ﹤0.01% 1923
2025
Q3 		$15.4M Buy
817,109
+170,474
+26% +$2.65M ﹤0.01% 2152
2025
Q2 		$7.1M Buy
646,635
+235,958
+57% +$2.18M ﹤0.01% 2552
2025
Q1 		$2.51M Buy
410,677
+47,408
+13% +$453K ﹤0.01% 2955
2024
Q4 		$5.97M Buy
+363,269
New +$8.11M ﹤0.01% 2658

Other funds holding UPB

Fidelity Investments
Fidelity Investments Boston, Massachusetts $1.9T AUM 41.92% 1-Year Est. Return
O
OrbiMed New York $5.05B AUM 125.28% 1-Year Est. Return
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
DC
Decheng Capital Menlo Park, California $661M AUM 299.97% 1-Year Est. Return
ES
Enavate Sciences Menlo Park, California $352M AUM 220.14% 1-Year Est. Return
VCM
Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM
YIH
Y-Intercept (HK) Hong Kong $5.05B AUM 17.89% 1-Year Est. Return
Federated Hermes
Federated Hermes Pittsburgh, Pennsylvania $61.5B AUM 30.7% 1-Year Est. Return
Millennium Management
Millennium Management New York $240B AUM 35.51% 1-Year Est. Return
SAM
SEB Asset Management Stockholm $23.4B AUM

Geode Capital Management's UPB Position: Q1 2026 in Review

Geode Capital Management increased its Upstream Bio Inc (UPB) stake by 12% in Q1 2026, buying an estimated $1.78M and bringing the position to 950,617 shares worth $8.56M. The position accounts for ﹤0.01% of the portfolio, ranked #2466.

Geode Capital Management first reported a position in UPB in Q4 2024 and has held it in 6 quarters since. The position peaked at $23.1M in Q4 2025. 140 funds tracked by Wall St. Rank hold UPB as of Q1 2026.

  • Geode Capital Management held 950,617 shares of Upstream Bio Inc worth $8.56M as of Q1 2026.
  • Geode Capital Management bought 98,709 Upstream Bio Inc shares in Q1 2026, an estimated $1.78M.
  • Upstream Bio Inc made up ﹤0.01% of Geode Capital Management's portfolio in Q1 2026, its #2466 holding.
  • Geode Capital Management first reported a position in Upstream Bio Inc in Q4 2024 and has held it in 6 quarters since.
  • Geode Capital Management's Upstream Bio Inc position peaked at $23.1M in Q4 2025.
  • 140 funds tracked by Wall St. Rank held Upstream Bio Inc as of Q1 2026.

Based on Geode Capital Management's 13F filing for Q1 2026, filed 15 May 2026.