Vanguard Capital Management
UPB

Vanguard Capital Management’s Upstream Bio Inc UPB Stock Holding History

Vanguard Capital Management’s Portfolio UPB Stock Details UPB Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q2 		$13M Buy
1,876,734
+3,160
+0.2% +$26.5K ﹤0.01% 2678
2026
Q1 		$16.9M Buy
+1,873,574
New +$33.7M ﹤0.01% 2443

Other funds holding UPB

Fidelity Investments
Fidelity Investments Boston, Massachusetts $2.3T AUM 54.33% 1-Year Est. Return
O
OrbiMed New York $5.4B AUM 163.13% 1-Year Est. Return
Norges Bank
Norges Bank Oslo, Norway $1T AUM
BlackRock
BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return
DC
Decheng Capital Menlo Park, California $732M AUM 275.56% 1-Year Est. Return
ES
Enavate Sciences Menlo Park, California $345M AUM 134.64% 1-Year Est. Return
Millennium Management
Millennium Management New York $276B AUM 44.8% 1-Year Est. Return
D.E. Shaw & Co
D.E. Shaw & Co New York $210B AUM 57.28% 1-Year Est. Return
JP Morgan Chase
JP Morgan Chase New York $1.81T AUM 41.13% 1-Year Est. Return
Qube Research & Technologies (QRT)
Qube Research & Technologies (QRT) London, United Kingdom $108B AUM 37.29% 1-Year Est. Return

Vanguard Capital Management's UPB Position: Q2 2026 in Review

Vanguard Capital Management increased its Upstream Bio Inc (UPB) stake by 0.17% in Q2 2026, buying an estimated $26.5K and bringing the position to 1,876,734 shares worth $13M. The position accounts for ﹤0.01% of the portfolio, ranked #2678.

Vanguard Capital Management first reported a position in UPB in Q1 2026 and has held it in 2 quarters since. The position peaked at $16.9M in Q1 2026. 149 funds tracked by Wall St. Rank hold UPB as of Q2 2026.

  • Vanguard Capital Management held 1,876,734 shares of Upstream Bio Inc worth $13M as of Q2 2026.
  • Vanguard Capital Management bought 3,160 Upstream Bio Inc shares in Q2 2026, an estimated $26.5K.
  • Upstream Bio Inc made up ﹤0.01% of Vanguard Capital Management's portfolio in Q2 2026, its #2678 holding.
  • Vanguard Capital Management first reported a position in Upstream Bio Inc in Q1 2026 and has held it in 2 quarters since.
  • Vanguard Capital Management's Upstream Bio Inc position peaked at $16.9M in Q1 2026.
  • 149 funds tracked by Wall St. Rank held Upstream Bio Inc as of Q2 2026.

Based on Vanguard Capital Management's 13F filing for Q2 2026, filed 13 Aug 2026.