TI
UPB

Trexquant Investment’s Upstream Bio Inc UPB Stock Holding History

Trexquant Investment’s Portfolio UPB Stock Details UPB Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$1.59M Buy
176,657
+145,608
+469% +$2.62M 0.01% 1080
2025
Q4 		$843K Buy
+31,049
New +$773K 0.01% 1230

Other funds holding UPB

Fidelity Investments
Fidelity Investments Boston, Massachusetts $1.9T AUM 41.92% 1-Year Est. Return
O
OrbiMed New York $5.05B AUM 125.28% 1-Year Est. Return
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
DC
Decheng Capital Menlo Park, California $661M AUM 299.97% 1-Year Est. Return
ES
Enavate Sciences Menlo Park, California $352M AUM 220.14% 1-Year Est. Return
VCM
Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM
YIH
Y-Intercept (HK) Hong Kong $5.05B AUM 17.89% 1-Year Est. Return
Federated Hermes
Federated Hermes Pittsburgh, Pennsylvania $61.5B AUM 30.7% 1-Year Est. Return
Geode Capital Management
Geode Capital Management Boston, Massachusetts $1.61T AUM 30.72% 1-Year Est. Return
Millennium Management
Millennium Management New York $240B AUM 35.51% 1-Year Est. Return

Trexquant Investment's UPB Position: Q1 2026 in Review

Trexquant Investment increased its Upstream Bio Inc (UPB) stake by 469% in Q1 2026, buying an estimated $2.62M and bringing the position to 176,657 shares worth $1.59M. The position accounts for 0.01% of the portfolio, ranked #1080.

Trexquant Investment first reported a position in UPB in Q4 2025 and has held it in 2 quarters since. 140 funds tracked by Wall St. Rank hold UPB as of Q1 2026.

  • Trexquant Investment held 176,657 shares of Upstream Bio Inc worth $1.59M as of Q1 2026.
  • Trexquant Investment bought 145,608 Upstream Bio Inc shares in Q1 2026, an estimated $2.62M.
  • Upstream Bio Inc made up 0.01% of Trexquant Investment's portfolio in Q1 2026, its #1080 holding.
  • Trexquant Investment first reported a position in Upstream Bio Inc in Q4 2025 and has held it in 2 quarters since.
  • 140 funds tracked by Wall St. Rank held Upstream Bio Inc as of Q1 2026.

Based on Trexquant Investment's 13F filing for Q1 2026, filed 15 May 2026.