Dimensional Fund Advisors
UPB

Dimensional Fund Advisors’s Upstream Bio Inc UPB Stock Holding History

Dimensional Fund Advisors’s Portfolio UPB Stock Details UPB Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q2 		$2.64M Buy
381,613
+301,611
+377% +$2.53M ﹤0.01% 2679
2026
Q1 		$719K Buy
+80,002
New +$1.44M ﹤0.01% 2897

Other funds holding UPB

Fidelity Investments
Fidelity Investments Boston, Massachusetts $2.3T AUM 54.33% 1-Year Est. Return
O
OrbiMed New York $5.4B AUM 163.13% 1-Year Est. Return
Norges Bank
Norges Bank Oslo, Norway $1T AUM
BlackRock
BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return
DC
Decheng Capital Menlo Park, California $732M AUM 275.56% 1-Year Est. Return
ES
Enavate Sciences Menlo Park, California $345M AUM 134.64% 1-Year Est. Return
Vanguard Capital Management
Vanguard Capital Management Malvern, Pennsylvania $4.68T AUM
Millennium Management
Millennium Management New York $276B AUM 44.8% 1-Year Est. Return
D.E. Shaw & Co
D.E. Shaw & Co New York $210B AUM 57.28% 1-Year Est. Return
JP Morgan Chase
JP Morgan Chase New York $1.81T AUM 41.13% 1-Year Est. Return

Dimensional Fund Advisors's UPB Position: Q2 2026 in Review

Dimensional Fund Advisors increased its Upstream Bio Inc (UPB) stake by 377% in Q2 2026, buying an estimated $2.53M and bringing the position to 381,613 shares worth $2.64M. The position accounts for ﹤0.01% of the portfolio, ranked #2679.

Dimensional Fund Advisors first reported a position in UPB in Q1 2026 and has held it in 2 quarters since. 148 funds tracked by Wall St. Rank hold UPB as of Q2 2026.

  • Dimensional Fund Advisors held 381,613 shares of Upstream Bio Inc worth $2.64M as of Q2 2026.
  • Dimensional Fund Advisors bought 301,611 Upstream Bio Inc shares in Q2 2026, an estimated $2.53M.
  • Upstream Bio Inc made up ﹤0.01% of Dimensional Fund Advisors's portfolio in Q2 2026, its #2679 holding.
  • Dimensional Fund Advisors first reported a position in Upstream Bio Inc in Q1 2026 and has held it in 2 quarters since.
  • 148 funds tracked by Wall St. Rank held Upstream Bio Inc as of Q2 2026.

Based on Dimensional Fund Advisors's 13F filing for Q2 2026, filed 11 Aug 2026.