Barclays’s Upstream Bio Inc UPB Stock Holding History

Barclays’s Portfolio UPB Stock Details UPB Fund Activity

Bought

Maintained

Sold

Quarter	Market Value	Status	Shares	Change in Stake	Trade Value	Portfolio Weight	Portfolio Position
2026 Q3	$1.04M	Buy	198,213 +169,005	+579%	+$1.11M	﹤0.01%	3021
2026 Q2	$202K	Buy	29,208 +4,488	+18%	+$37.6K	﹤0.01%	3690
2026 Q1	$222K	Sell	24,720 -499,779	-95%	-$8.99M	﹤0.01%	3629
2025 Q4	$14.2M	Buy	524,499 +439,184	+515%	+$10.9M	﹤0.01%	1443
2025 Q3	$1.6M	Sell	85,315 -11,675	-12%	-$181K	﹤0.01%	3034
2025 Q2	$1.06M	Buy	96,990 +71,997	+288%	+$665K	﹤0.01%	3300
2025 Q1	$153K	Sell	24,993 -2,024	-7%	-$19.3K	﹤0.01%	4193
2024 Q4	$444K	Buy	+27,017	New	+$603K	﹤0.01%	3894

Other funds holding UPB

Geode Capital Management Boston, Massachusetts $1.92T AUM 36.1% 1-Year Est. Return

SEB Asset Management Stockholm $27B AUM

Y-Intercept (HK) Hong Kong $4.52B AUM 6.6% 1-Year Est. Return

Dimensional Fund Advisors Austin, Texas $551B AUM 33.95% 1-Year Est. Return

Bank of New York Mellon New York $608B AUM 32.77% 1-Year Est. Return

ALPS Advisors Denver, Colorado $21.8B AUM 17.58% 1-Year Est. Return

Simplify Asset Management Las Vegas, Nevada $6.11B AUM 3.71% 1-Year Est. Return

Russell Investments Group London, United Kingdom $114B AUM 33.83% 1-Year Est. Return

Allspring Global Investments Charlotte, North Carolina $64.1B AUM 28.9% 1-Year Est. Return

Citigroup New York $308B AUM 40.94% 1-Year Est. Return

Barclays's UPB Position: Q3 2026 in Review

Barclays increased its Upstream Bio Inc (UPB) stake by 579% in Q3 2026, buying an estimated $1.11M and bringing the position to 198,213 shares worth $1.04M. The position accounts for ﹤0.01% of the portfolio, ranked #3021.

Barclays first reported a position in UPB in Q4 2024 and has held it in 8 quarters since. The position peaked at $14.2M in Q4 2025. 38 funds tracked by Wall St. Rank hold UPB as of Q3 2026.

Barclays held 198,213 shares of Upstream Bio Inc worth $1.04M as of Q3 2026.
Barclays bought 169,005 Upstream Bio Inc shares in Q3 2026, an estimated $1.11M.
Upstream Bio Inc made up ﹤0.01% of Barclays's portfolio in Q3 2026, its #3021 holding.
Barclays first reported a position in Upstream Bio Inc in Q4 2024 and has held it in 8 quarters since.
Barclays's Upstream Bio Inc position peaked at $14.2M in Q4 2025.
38 funds tracked by Wall St. Rank held Upstream Bio Inc as of Q3 2026.

Based on Barclays's 13F filing for Q3 2026, filed 6 Nov 2026.