UBS Group
UPB

UBS Group’s Upstream Bio Inc UPB Stock Holding History

UBS Group’s Portfolio UPB Stock Details UPB Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$2.08M Sell
231,254
-1,574,989
-87% -$28.3M ﹤0.01% 4940
2025
Q4 		$49M Buy
1,806,243
+1,533,972
+563% +$38.2M 0.01% 1648
2025
Q3 		$5.12M Buy
272,271
+39,384
+17% +$612K ﹤0.01% 4012
2025
Q2 		$2.56M Buy
232,887
+101,336
+77% +$936K ﹤0.01% 4562
2025
Q1 		$805K Sell
131,551
-29,961
-19% -$286K ﹤0.01% 5466
2024
Q4 		$2.66M Buy
+161,512
New +$3.61M ﹤0.01% 4444

Other funds holding UPB

Fidelity Investments
Fidelity Investments Boston, Massachusetts $1.9T AUM 41.92% 1-Year Est. Return
O
OrbiMed New York $5.05B AUM 125.28% 1-Year Est. Return
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
DC
Decheng Capital Menlo Park, California $661M AUM 299.97% 1-Year Est. Return
ES
Enavate Sciences Menlo Park, California $352M AUM 220.14% 1-Year Est. Return
VCM
Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM
YIH
Y-Intercept (HK) Hong Kong $5.05B AUM 17.89% 1-Year Est. Return
Federated Hermes
Federated Hermes Pittsburgh, Pennsylvania $61.5B AUM 30.7% 1-Year Est. Return
Geode Capital Management
Geode Capital Management Boston, Massachusetts $1.61T AUM 30.72% 1-Year Est. Return
Millennium Management
Millennium Management New York $240B AUM 35.51% 1-Year Est. Return

UBS Group's UPB Position: Q1 2026 in Review

UBS Group reduced its Upstream Bio Inc (UPB) stake by 87% in Q1 2026, selling an estimated $28.3M and leaving 231,254 shares worth $2.08M. The position accounts for ﹤0.01% of the portfolio, ranked #4940.

UBS Group first reported a position in UPB in Q4 2024 and has held it in 6 quarters since. The position peaked at $49M in Q4 2025. 140 funds tracked by Wall St. Rank hold UPB as of Q1 2026.

  • UBS Group held 231,254 shares of Upstream Bio Inc worth $2.08M as of Q1 2026.
  • UBS Group sold 1,574,989 Upstream Bio Inc shares in Q1 2026, an estimated $28.3M.
  • Upstream Bio Inc made up ﹤0.01% of UBS Group's portfolio in Q1 2026, its #4940 holding.
  • UBS Group first reported a position in Upstream Bio Inc in Q4 2024 and has held it in 6 quarters since.
  • UBS Group's Upstream Bio Inc position peaked at $49M in Q4 2025.
  • 140 funds tracked by Wall St. Rank held Upstream Bio Inc as of Q1 2026.

Based on UBS Group's 13F filing for Q1 2026, filed 5 May 2026.