Alyeska Investment Group’s Upstream Bio, Inc. Common Stock UPB Stock Holding History

Bought

Maintained

Sold

Quarter	Market Value	Status	Shares	Shares Change %	Capital Flow	Portfolio Weight	Portfolio Position
2025 Q2	$933K	Hold	85,000	–	–	﹤0.01%	507
2025 Q1	$520K	Hold	85,000	–	–	﹤0.01%	462
2024 Q4	$1.4M	Buy	+85,000	New	+$1.4M	0.01%	479