Vanguard Fiduciary Trust
UPB

Vanguard Fiduciary Trust’s Upstream Bio Inc UPB Stock Holding History

Vanguard Fiduciary Trust’s Portfolio UPB Stock Details UPB Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q2 		$1.66M Buy
239,616
+15,459
+7% +$130K ﹤0.01% 2776
2026
Q1 		$2.02M Buy
+224,157
New +$4.03M ﹤0.01% 2564

Other funds holding UPB

Fidelity Investments
Fidelity Investments Boston, Massachusetts $2.3T AUM 54.33% 1-Year Est. Return
O
OrbiMed New York $5.4B AUM 163.13% 1-Year Est. Return
Norges Bank
Norges Bank Oslo, Norway $1T AUM
BlackRock
BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return
DC
Decheng Capital Menlo Park, California $732M AUM 275.56% 1-Year Est. Return
ES
Enavate Sciences Menlo Park, California $345M AUM 134.64% 1-Year Est. Return
Vanguard Capital Management
Vanguard Capital Management Malvern, Pennsylvania $4.68T AUM
Millennium Management
Millennium Management New York $276B AUM 44.8% 1-Year Est. Return
D.E. Shaw & Co
D.E. Shaw & Co New York $210B AUM 57.28% 1-Year Est. Return
JP Morgan Chase
JP Morgan Chase New York $1.81T AUM 41.13% 1-Year Est. Return

Vanguard Fiduciary Trust's UPB Position: Q2 2026 in Review

Vanguard Fiduciary Trust increased its Upstream Bio Inc (UPB) stake by 6.9% in Q2 2026, buying an estimated $130K and bringing the position to 239,616 shares worth $1.66M. The position accounts for ﹤0.01% of the portfolio, ranked #2776.

Vanguard Fiduciary Trust first reported a position in UPB in Q1 2026 and has held it in 2 quarters since. The position peaked at $2.02M in Q1 2026. 149 funds tracked by Wall St. Rank hold UPB as of Q2 2026.

  • Vanguard Fiduciary Trust held 239,616 shares of Upstream Bio Inc worth $1.66M as of Q2 2026.
  • Vanguard Fiduciary Trust bought 15,459 Upstream Bio Inc shares in Q2 2026, an estimated $130K.
  • Upstream Bio Inc made up ﹤0.01% of Vanguard Fiduciary Trust's portfolio in Q2 2026, its #2776 holding.
  • Vanguard Fiduciary Trust first reported a position in Upstream Bio Inc in Q1 2026 and has held it in 2 quarters since.
  • Vanguard Fiduciary Trust's Upstream Bio Inc position peaked at $2.02M in Q1 2026.
  • 149 funds tracked by Wall St. Rank held Upstream Bio Inc as of Q2 2026.

Based on Vanguard Fiduciary Trust's 13F filing for Q2 2026, filed 13 Aug 2026.