Northern Trust’s Upstream Bio, Inc. Common Stock UPB Stock Holding History

Bought

Maintained

Sold

Quarter	Market Value	Status	Shares	Shares Change %	Capital Flow	Portfolio Weight	Portfolio Position
2025 Q2	$2.52M	Buy	229,303 +91,532	+66%	+$1.01M	﹤0.01%	2854
2025 Q1	$843K	Sell	137,771 -5,950	-4%	-$36.4K	﹤0.01%	3352
2024 Q4	$2.36M	Buy	+143,721	New	+$2.36M	﹤0.01%	2929