|
1
|
RA Capital Management
Boston,
Massachusetts
|
$258M
|
–
|
–
|
–
|
|
|
2
|
Fidelity Investments
Boston,
Massachusetts
|
$205M
|
+$123K
|
+4,670
|
+0.1%
|
|
|
3
|
Janus Henderson Group
London,
|
$103M
|
-$3.63M
|
-137,760
|
-3%
|
|
|
4
|
|
$78.6M
|
+$14M
|
+529,888
|
+18%
|
|
|
5
|
Paradigm Biocapital Advisors
New York
|
$67.5M
|
-$10.8M
|
-409,651
|
-12%
|
|
|
6
|
Adage Capital Partners
Boston,
Massachusetts
|
$58.3M
|
-$29.8M
|
-1,129,574
|
-31%
|
|
|
7
|
Vanguard Group
Malvern,
Pennsylvania
|
$50.6M
|
-$2.35M
|
-89,232
|
-4%
|
|
|
8
|
Point72 Asset Management
Stamford,
Connecticut
|
$49.5M
|
+$46.6M
|
+1,767,238
|
+469%
|
|
|
9
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$41.4M
|
+$10.6M
|
+400,601
|
+29%
|
|
|
10
|
Cormorant Asset Management
Boston,
Massachusetts
|
$34.6M
|
-$13.2M
|
-500,000
|
-25%
|
|
|
11
|
EcoR1 Capital
San Francisco,
California
|
$34M
|
–
|
–
|
–
|
|
|
12
|
State Street
Boston,
Massachusetts
|
$32.1M
|
+$438K
|
+16,611
|
+1%
|
|
|
13
|
Woodline Partners
San Francisco,
California
|
$28.7M
|
-$5.67M
|
-215,157
|
-15%
|
|
|
14
|
Citadel Advisors
Miami,
Florida
|
$28.4M
|
+$13.8M
|
+524,462
|
+74%
|
|
|
15
|
|
$28M
|
+$11.9M
|
+451,734
|
+60%
|
|
|
16
|
Franklin Resources
San Mateo,
California
|
$24.7M
|
-$3.09M
|
-117,284
|
-10%
|
|
|
17
|
Logos Global Management
San Francisco,
California
|
$23.1M
|
-$17.1M
|
-650,000
|
-39%
|
|
|
18
|
Geode Capital Management
Boston,
Massachusetts
|
$20.8M
|
+$3.2M
|
+121,403
|
+16%
|
|
|
19
|
Bank of America
Charlotte,
North Carolina
|
$19.9M
|
+$2.9M
|
+110,097
|
+15%
|
|
|
20
|
Prosight Management
Dallas,
Texas
|
$19.7M
|
+$4.32M
|
+164,003
|
+24%
|
|
|
21
|
Readystate Asset Management
Chicago,
Illinois
|
$16.1M
|
+$11.1M
|
+419,396
|
+152%
|
|
|
22
|
Pictet Asset Management
Carouge,
Switzerland
|
$15.5M
|
+$392K
|
+14,880
|
+2%
|
|
|
23
|
MPM BioImpact
Boston,
Massachusetts
|
$14.2M
|
+$1.24M
|
+47,089
|
+8%
|
|
|
24
|
Wellington Management Group
Boston,
Massachusetts
|
$11.4M
|
+$2.61M
|
+98,884
|
+25%
|
|
|
25
|
Caption Management
Oklahoma City,
Oklahoma
|
$10.6M
|
+$10.9M
|
+412,569
|
+928%
|
|
