|
1
|
RA Capital Management
Boston,
Massachusetts
|
$117M
|
–
|
–
|
–
|
|
|
2
|
Fidelity Investments
Boston,
Massachusetts
|
$84.6M
|
+$5.63M
|
+421,688
|
+7%
|
|
|
3
|
|
$38.4M
|
–
|
–
|
–
|
|
|
4
|
Janus Henderson Group
London,
|
$26.5M
|
-$2.24M
|
-167,753
|
-8%
|
|
|
5
|
Citadel Advisors
Miami,
Florida
|
$25.1M
|
-$2.89K
|
-216
|
-0%
|
|
|
6
|
BVF Inc
San Francisco,
California
|
$19.9M
|
–
|
–
|
–
|
|
|
7
|
EcoR1 Capital
San Francisco,
California
|
$19.2M
|
–
|
–
|
–
|
|
|
8
|
|
$16.9M
|
+$561K
|
+41,994
|
+3%
|
|
|
9
|
Vanguard Group
Malvern,
Pennsylvania
|
$10.3M
|
+$1.48M
|
+110,834
|
+17%
|
|
|
10
|
5AM Venture Management
San Francisco,
California
|
$6.04M
|
–
|
–
|
–
|
|
|
11
|
Woodline Partners
San Francisco,
California
|
$5.42M
|
+$1.52M
|
+113,798
|
+40%
|
|
|
12
|
Adage Capital Partners
Boston,
Massachusetts
|
$5.42M
|
–
|
–
|
–
|
|
|
13
|
Samsara BioCapital
Palo Alto,
California
|
$4.88M
|
–
|
–
|
–
|
|
|
14
|
Geode Capital Management
Boston,
Massachusetts
|
$4.53M
|
+$680K
|
+50,901
|
+18%
|
|
|
15
|
State Street
Boston,
Massachusetts
|
$3.58M
|
+$2.47K
|
+185
|
+0.1%
|
|
|
16
|
|
$1.92M
|
+$1.52M
|
+113,747
|
+410%
|
|
|
17
|
Northern Trust
Chicago,
Illinois
|
$1.85M
|
+$42.8K
|
+3,207
|
+2%
|
|
|
18
|
|
$1.43M
|
-$601K
|
-45,000
|
-30%
|
|
|
19
|
|
$1.42M
|
+$21K
|
+1,575
|
+2%
|
|
|
20
|
Nuveen
Charlotte,
North Carolina
|
$987K
|
-$26.7K
|
-1,996
|
-3%
|
|
|
21
|
Bank of New York Mellon
New York
|
$679K
|
+$103K
|
+7,707
|
+18%
|
|
|
22
|
DekaBank Deutsche Girozentrale
Frankfurt,
Germany
|
$669K
|
–
|
–
|
–
|
|
|
23
|
Charles Schwab
San Francisco,
California
|
$631K
|
+$54.2K
|
+4,053
|
+10%
|
|
|
24
|
Parkwood LLC
Cleveland,
Ohio
|
$452K
|
-$5.32K
|
-398
|
-1%
|
|
|
25
|
RhumbLine Advisers
Boston,
Massachusetts
|
$346K
|
+$22.4K
|
+1,678
|
+7%
|
|
