|
1
|
RA Capital Management
Boston,
Massachusetts
|
$188M
|
–
|
–
|
–
|
|
|
2
|
Fidelity Investments
Boston,
Massachusetts
|
$78.2M
|
+$51M
|
+1,771,867
|
+96%
|
|
|
3
|
|
$75M
|
–
|
–
|
–
|
|
|
4
|
Janus Henderson Group
London,
|
$51.4M
|
-$7.24M
|
-251,803
|
-9%
|
|
|
5
|
Citadel Advisors
Miami,
Florida
|
$39.6M
|
-$790K
|
-27,466
|
-1%
|
|
|
6
|
EcoR1 Capital
San Francisco,
California
|
$30.5M
|
–
|
–
|
–
|
|
|
7
|
BVF Inc
San Francisco,
California
|
$22M
|
-$4.59M
|
-159,367
|
-14%
|
|
|
8
|
|
$17.3M
|
+$19.9M
|
+691,831
|
+629%
|
|
|
9
|
Vanguard Group
Malvern,
Pennsylvania
|
$11.5M
|
+$14.4M
|
+501,266
|
+1,730%
|
|
|
10
|
5AM Venture Management
San Francisco,
California
|
$9.65M
|
–
|
–
|
–
|
|
|
11
|
Samsara BioCapital
Palo Alto,
California
|
$8.91M
|
-$5.64M
|
-196,078
|
-32%
|
|
|
12
|
Adage Capital Partners
Boston,
Massachusetts
|
$8.65M
|
-$1.44M
|
-50,000
|
-11%
|
|
|
13
|
Woodline Partners
San Francisco,
California
|
$6.49M
|
-$985K
|
-34,229
|
-10%
|
|
|
14
|
Logos Global Management
San Francisco,
California
|
$4.81M
|
-$8.63M
|
-300,000
|
-55%
|
|
|
15
|
Geode Capital Management
Boston,
Massachusetts
|
$4.58M
|
+$5.46M
|
+189,863
|
+862%
|
|
|
16
|
State Street
Boston,
Massachusetts
|
$3.78M
|
+$5.02M
|
+174,644
|
New
|
|
|
17
|
Northern Trust
Chicago,
Illinois
|
$2.53M
|
+$3.37M
|
+116,961
|
New
|
|
|
18
|
SG Americas Securities
New York
|
$1.42M
|
+$1.88M
|
+65,414
|
New
|
|
|
19
|
Parametric Portfolio Associates
Seattle,
Washington
|
$1.28M
|
+$1.71M
|
+59,366
|
New
|
|
|
20
|
|
$998K
|
+$1.33M
|
+46,156
|
New
|
|
|
21
|
Janney Montgomery Scott
Philadelphia,
Pennsylvania
|
$884K
|
+$1.18M
|
+40,860
|
New
|
|
|
22
|
Charles Schwab
San Francisco,
California
|
$705K
|
+$937K
|
+32,576
|
New
|
|
|
23
|
Bank of New York Mellon
New York
|
$681K
|
+$906K
|
+31,473
|
New
|
|
|
24
|
Parkwood LLC
Cleveland,
Ohio
|
$449K
|
+$598K
|
+20,777
|
New
|
|
|
25
|
Nuveen
Charlotte,
North Carolina
|
$421K
|
+$560K
|
+19,457
|
New
|
|
