|
1
|
RA Capital Management
Boston,
Massachusetts
|
$103M
|
–
|
–
|
–
|
|
|
2
|
Fidelity Investments
Boston,
Massachusetts
|
$60.1M
|
-$1.04M
|
-77,848
|
-2%
|
|
|
3
|
BVF Inc
San Francisco,
California
|
$48.7M
|
+$33.7M
|
+2,521,268
|
+159%
|
|
|
4
|
|
$33.7M
|
–
|
–
|
–
|
|
|
5
|
Citadel Advisors
Miami,
Florida
|
$25.1M
|
+$3.51M
|
+262,548
|
+14%
|
|
|
6
|
Janus Henderson Group
London,
|
$25M
|
+$3.21M
|
+240,262
|
+13%
|
|
|
7
|
|
$14.2M
|
+$801K
|
+59,943
|
+5%
|
|
|
8
|
Adage Capital Partners
Boston,
Massachusetts
|
$10.7M
|
–
|
–
|
–
|
|
|
9
|
Vanguard Group
Malvern,
Pennsylvania
|
$9.04M
|
-$143K
|
-10,665
|
-1%
|
|
|
10
|
EcoR1 Capital
San Francisco,
California
|
$5.37M
|
-$45.3M
|
-3,385,896
|
-88%
|
|
|
11
|
Geode Capital Management
Boston,
Massachusetts
|
$4.48M
|
+$303K
|
+22,640
|
+6%
|
|
|
12
|
Samsara BioCapital
Palo Alto,
California
|
$4.28M
|
–
|
–
|
–
|
|
|
13
|
State Street
Boston,
Massachusetts
|
$3.95M
|
+$454K
|
+33,961
|
+11%
|
|
|
14
|
Northern Trust
Chicago,
Illinois
|
$2.22M
|
+$632K
|
+47,319
|
+34%
|
|
|
15
|
|
$1.82M
|
+$318K
|
+23,779
|
+18%
|
|
|
16
|
Millennium Management
New York
|
$1.64M
|
+$1.39M
|
+104,143
|
+305%
|
|
|
17
|
Woodline Partners
San Francisco,
California
|
$1.63M
|
–
|
–
|
–
|
|
|
18
|
|
$723K
|
+$814K
|
+60,933
|
New
|
|
|
19
|
Nuveen
Charlotte,
North Carolina
|
$697K
|
+$172K
|
+12,842
|
+28%
|
|
|
20
|
Bank of New York Mellon
New York
|
$630K
|
-$561
|
-42
|
-0.1%
|
|
|
21
|
DekaBank Deutsche Girozentrale
Frankfurt,
Germany
|
$571K
|
–
|
–
|
–
|
|
|
22
|
Charles Schwab
San Francisco,
California
|
$547K
|
+$9.74K
|
+729
|
+2%
|
|
|
23
|
|
$330K
|
+$195K
|
+14,613
|
+111%
|
|
|
24
|
RhumbLine Advisers
Boston,
Massachusetts
|
$318K
|
-$949
|
-71
|
-0.3%
|
|
|
25
|
Swiss National Bank
Zurich,
Switzerland
|
$271K
|
-$56.1K
|
-4,200
|
-16%
|
|
