|
1
|
RA Capital Management
Boston,
Massachusetts
|
$555M
|
+$63.5M
|
+1,200,000
|
+13%
|
|
|
2
|
Fidelity Investments
Boston,
Massachusetts
|
$464M
|
+$44.7M
|
+845,266
|
+11%
|
|
|
3
|
Janus Henderson Group
London,
|
$191M
|
+$55M
|
+1,038,996
|
+41%
|
|
|
4
|
Paradigm Biocapital Advisors
New York
|
$188M
|
+$59M
|
+1,115,412
|
+46%
|
|
|
5
|
Adage Capital Partners
Boston,
Massachusetts
|
$164M
|
+$52.2M
|
+986,750
|
+48%
|
|
|
6
|
|
$146M
|
+$16M
|
+303,177
|
+13%
|
|
|
7
|
Vanguard Group
Malvern,
Pennsylvania
|
$114M
|
+$15.3M
|
+288,402
|
+16%
|
|
|
8
|
Cormorant Asset Management
Boston,
Massachusetts
|
$112M
|
+$55.5M
|
+1,050,000
|
+100%
|
|
|
9
|
Woodline Partners
San Francisco,
California
|
$99.2M
|
+$13.3M
|
+251,924
|
+16%
|
|
|
10
|
EcoR1 Capital
San Francisco,
California
|
$78.7M
|
–
|
–
|
–
|
|
|
11
|
Citadel Advisors
Miami,
Florida
|
$72.9M
|
+$18.6M
|
+351,110
|
+35%
|
|
|
12
|
State Street
Boston,
Massachusetts
|
$67.9M
|
-$4.93M
|
-93,229
|
-7%
|
|
|
13
|
Lord, Abbett & Co
Jersey City,
New Jersey
|
$67.9M
|
+$29.8M
|
+564,322
|
+80%
|
|
|
14
|
Logos Global Management
San Francisco,
California
|
$66.9M
|
+$13.2M
|
+250,000
|
+25%
|
|
|
15
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$59.4M
|
+$50.3M
|
+950,557
|
+596%
|
|
|
16
|
Holocene Advisors
New York
|
$54.3M
|
+$53.7M
|
+1,015,060
|
New
|
|
|
17
|
Perceptive Advisors
New York
|
$43.8M
|
+$43.3M
|
+817,895
|
New
|
|
|
18
|
Bank of America
Charlotte,
North Carolina
|
$42.6M
|
+$38.7M
|
+731,962
|
+1,166%
|
|
|
19
|
|
$40.6M
|
-$26.4M
|
-500,000
|
-40%
|
|
|
20
|
Avidity Partners Management
Dallas,
Texas
|
$39.7M
|
+$9.52M
|
+179,900
|
+32%
|
|
|
21
|
Geode Capital Management
Boston,
Massachusetts
|
$38.3M
|
+$2.77M
|
+52,362
|
+8%
|
|
|
22
|
Point72 Asset Management
Stamford,
Connecticut
|
$33.3M
|
+$11.9M
|
+225,508
|
+57%
|
|
|
23
|
Wellington Management Group
Boston,
Massachusetts
|
$28.7M
|
+$27.6M
|
+520,898
|
+3,593%
|
|
|
24
|
Driehaus Capital Management
Chicago,
Illinois
|
$27.6M
|
+$27.3M
|
+515,646
|
New
|
|
|
25
|
Franklin Resources
San Mateo,
California
|
$26.6M
|
+$25.3M
|
+478,304
|
+2,520%
|
|
