|
1
|
RA Capital Management
Boston,
Massachusetts
|
$384M
|
–
|
–
|
–
|
|
|
2
|
Fidelity Investments
Boston,
Massachusetts
|
$326M
|
+$1.34M
|
+28,591
|
+0.4%
|
|
|
3
|
|
$125M
|
-$60.8M
|
-1,295,725
|
-30%
|
|
|
4
|
|
$98.2M
|
+$30.5M
|
+650,016
|
+38%
|
|
|
5
|
Adage Capital Partners
Boston,
Massachusetts
|
$97.5M
|
-$21M
|
-447,776
|
-16%
|
|
|
6
|
Janus Henderson Group
London,
|
$75.4M
|
-$7.69M
|
-163,703
|
-8%
|
|
|
7
|
Paradigm Biocapital Advisors
New York
|
$65.5M
|
+$73.5M
|
+1,564,452
|
New
|
|
|
8
|
Vanguard Group
Malvern,
Pennsylvania
|
$65.4M
|
+$9.57M
|
+203,798
|
+15%
|
|
|
9
|
Citadel Advisors
Miami,
Florida
|
$65.2M
|
-$37.2M
|
-793,122
|
-34%
|
|
|
10
|
EcoR1 Capital
San Francisco,
California
|
$61.6M
|
+$69M
|
+1,469,818
|
New
|
|
|
11
|
State Street
Boston,
Massachusetts
|
$58.7M
|
+$47M
|
+1,001,767
|
+251%
|
|
|
12
|
Cormorant Asset Management
Boston,
Massachusetts
|
$44M
|
+$14.1M
|
+300,000
|
+40%
|
|
|
13
|
Avidity Partners Management
Dallas,
Texas
|
$35.2M
|
+$21.4M
|
+455,974
|
+119%
|
|
|
14
|
Logos Global Management
San Francisco,
California
|
$31.4M
|
+$28.2M
|
+600,000
|
+400%
|
|
|
15
|
Vestal Point Capital
New York
|
$30.4M
|
+$34M
|
+725,000
|
New
|
|
|
16
|
Lord, Abbett & Co
Jersey City,
New Jersey
|
$29.4M
|
+$7.52M
|
+160,234
|
+30%
|
|
|
17
|
Geode Capital Management
Boston,
Massachusetts
|
$26.1M
|
+$7.35M
|
+156,557
|
+33%
|
|
|
18
|
BVF Inc
San Francisco,
California
|
$18.5M
|
-$116M
|
-2,478,290
|
-85%
|
|
|
19
|
Nuveen
Charlotte,
North Carolina
|
$16.6M
|
+$14.9M
|
+318,281
|
+405%
|
|
|
20
|
|
$14.4M
|
-$117K
|
-2,499
|
-0.7%
|
|
|
21
|
|
$13.6M
|
+$1.33M
|
+28,312
|
+10%
|
|
|
22
|
Woodline Partners
San Francisco,
California
|
$12.6M
|
+$12.7M
|
+270,977
|
+908%
|
|
|
23
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$10.6M
|
+$10.9M
|
+232,762
|
+1,188%
|
|
|
24
|
Schonfeld Strategic Advisors
New York
|
$10.2M
|
+$4.22M
|
+89,810
|
+59%
|
|
|
25
|
|
$8.5M
|
+$7.18M
|
+153,000
|
+306%
|
|
