|
1
|
RA Capital Management
Boston,
Massachusetts
|
$302M
|
+$31.1M
|
+824,041
|
+8%
|
|
|
2
|
Fidelity Investments
Boston,
Massachusetts
|
$240M
|
+$8.07M
|
+214,131
|
+2%
|
|
|
3
|
Janus Henderson Group
London,
|
$134M
|
+$39M
|
+1,035,690
|
+29%
|
|
|
4
|
Adage Capital Partners
Boston,
Massachusetts
|
$98.7M
|
+$22.3M
|
+592,824
|
+19%
|
|
|
5
|
Paradigm Biocapital Advisors
New York
|
$89.9M
|
-$7.01M
|
-186,077
|
-5%
|
|
|
6
|
|
$77.6M
|
+$5.55M
|
+147,146
|
+5%
|
|
|
7
|
Vanguard Group
Malvern,
Pennsylvania
|
$61.5M
|
+$5.37M
|
+142,328
|
+7%
|
|
|
8
|
Cormorant Asset Management
Boston,
Massachusetts
|
$54M
|
-$3.77M
|
-100,000
|
-5%
|
|
|
9
|
Logos Global Management
San Francisco,
California
|
$44.5M
|
+$15.1M
|
+400,000
|
+32%
|
|
|
10
|
EcoR1 Capital
San Francisco,
California
|
$39.7M
|
–
|
–
|
–
|
|
|
11
|
Woodline Partners
San Francisco,
California
|
$39.3M
|
-$14.9M
|
-395,092
|
-21%
|
|
|
12
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$37.6M
|
+$10.7M
|
+282,848
|
+25%
|
|
|
13
|
State Street
Boston,
Massachusetts
|
$37M
|
+$3.9M
|
+103,548
|
+8%
|
|
|
14
|
Franklin Resources
San Mateo,
California
|
$32M
|
+$26M
|
+689,192
|
+139%
|
|
|
15
|
Perceptive Advisors
New York
|
$26.2M
|
+$5.75M
|
+152,517
|
+19%
|
|
|
16
|
Geode Capital Management
Boston,
Massachusetts
|
$21.1M
|
+$2.49M
|
+65,953
|
+9%
|
|
|
17
|
|
$20.5M
|
–
|
–
|
–
|
|
|
18
|
Bank of America
Charlotte,
North Carolina
|
$20.2M
|
-$1.71M
|
-45,435
|
-6%
|
|
|
19
|
Citadel Advisors
Miami,
Florida
|
$19.1M
|
-$24.7M
|
-654,214
|
-48%
|
|
|
20
|
Prosight Management
Dallas,
Texas
|
$18.6M
|
+$13.6M
|
+360,133
|
+109%
|
|
|
21
|
Lord, Abbett & Co
Jersey City,
New Jersey
|
$18M
|
-$22.6M
|
-599,922
|
-47%
|
|
|
22
|
First Light Asset Management
Edina,
Minnesota
|
$17.8M
|
+$13M
|
+345,042
|
+110%
|
|
|
23
|
Pictet Asset Management
Carouge,
Switzerland
|
$17.7M
|
+$10.2M
|
+271,808
|
+71%
|
|
|
24
|
MPM BioImpact
Boston,
Massachusetts
|
$15.3M
|
+$12.7M
|
+337,193
|
+147%
|
|
|
25
|
UBS Group
Zurich,
Switzerland
|
$13.2M
|
+$9.93M
|
+263,390
|
+117%
|
|
