|
1
|
RA Capital Management
Boston,
Massachusetts
|
$92.4M
|
+$5.71M
|
+495,008
|
+6%
|
|
|
2
|
Fidelity Investments
Boston,
Massachusetts
|
$64M
|
+$14.9M
|
+1,288,526
|
+25%
|
|
|
3
|
BVF Inc
San Francisco,
California
|
$46.2M
|
+$5.45M
|
+472,873
|
+12%
|
|
|
4
|
Citadel Advisors
Miami,
Florida
|
$34.6M
|
+$15.2M
|
+1,315,635
|
+62%
|
|
|
5
|
|
$33.4M
|
+$5.55M
|
+481,541
|
+17%
|
|
|
6
|
Janus Henderson Group
London,
|
$20.8M
|
-$483K
|
-41,870
|
-2%
|
|
|
7
|
|
$16.5M
|
+$5.13M
|
+444,991
|
+37%
|
|
|
8
|
Adage Capital Partners
Boston,
Massachusetts
|
$11.6M
|
+$2.88M
|
+250,000
|
+28%
|
|
|
9
|
Vanguard Group
Malvern,
Pennsylvania
|
$9.5M
|
+$2.08M
|
+180,291
|
+24%
|
|
|
10
|
Geode Capital Management
Boston,
Massachusetts
|
$3.9M
|
+$110K
|
+9,579
|
+3%
|
|
|
11
|
Samsara BioCapital
Palo Alto,
California
|
$3.63M
|
–
|
–
|
–
|
|
|
12
|
State Street
Boston,
Massachusetts
|
$3.34M
|
-$11.8K
|
-1,019
|
-0.3%
|
|
|
13
|
Northern Trust
Chicago,
Illinois
|
$1.94M
|
+$62.2K
|
+5,395
|
+3%
|
|
|
14
|
Alyeska Investment Group
Chicago,
Illinois
|
$1.76M
|
+$2.02M
|
+175,000
|
New
|
|
|
15
|
|
$1.5M
|
-$55.7K
|
-4,827
|
-3%
|
|
|
16
|
Bank of Montreal
Toronto,
Ontario, Canada
|
$1.08M
|
+$1.14M
|
+98,429
|
New
|
|
|
17
|
Millennium Management
New York
|
$1.01M
|
-$434K
|
-37,634
|
-27%
|
|
|
18
|
Woodline Partners
San Francisco,
California
|
$864K
|
-$595K
|
-51,592
|
-38%
|
|
|
19
|
Nuveen
Charlotte,
North Carolina
|
$672K
|
+$91.8K
|
+7,957
|
+14%
|
|
|
20
|
Bank of New York Mellon
New York
|
$535K
|
–
|
–
|
–
|
|
|
21
|
Charles Schwab
San Francisco,
California
|
$491K
|
+$30.3K
|
+2,629
|
+6%
|
|
|
22
|
DekaBank Deutsche Girozentrale
Frankfurt,
Germany
|
$484K
|
–
|
–
|
–
|
|
|
23
|
Bank of America
Charlotte,
North Carolina
|
$308K
|
+$108K
|
+9,393
|
+44%
|
|
|
24
|
RhumbLine Advisers
Boston,
Massachusetts
|
$267K
|
-$2.84K
|
-246
|
-0.9%
|
|
|
25
|
Renaissance Technologies
New York
|
$263K
|
+$130K
|
+11,300
|
+76%
|
|
