|
1
|
RA Capital Management
Boston,
Massachusetts
|
$416M
|
–
|
–
|
–
|
|
|
2
|
Fidelity Investments
Boston,
Massachusetts
|
$355M
|
+$2.05M
|
+47,075
|
+0.6%
|
|
|
3
|
Janus Henderson Group
London,
|
$115M
|
+$31.4M
|
+721,563
|
+40%
|
|
|
4
|
|
$110M
|
+$3.42M
|
+78,629
|
+3%
|
|
|
5
|
Paradigm Biocapital Advisors
New York
|
$109M
|
+$36.4M
|
+836,122
|
+53%
|
|
|
6
|
Adage Capital Partners
Boston,
Massachusetts
|
$94.3M
|
-$11M
|
-252,896
|
-11%
|
|
|
7
|
Vanguard Group
Malvern,
Pennsylvania
|
$84M
|
+$12.4M
|
+286,172
|
+18%
|
|
|
8
|
Woodline Partners
San Francisco,
California
|
$72.7M
|
+$56.5M
|
+1,299,438
|
+432%
|
|
|
9
|
EcoR1 Capital
San Francisco,
California
|
$66.8M
|
–
|
–
|
–
|
|
|
10
|
State Street
Boston,
Massachusetts
|
$61.8M
|
-$1.74M
|
-40,056
|
-3%
|
|
|
11
|
|
$57.2M
|
-$74.9M
|
-1,721,262
|
-58%
|
|
|
12
|
Cormorant Asset Management
Boston,
Massachusetts
|
$47.7M
|
–
|
–
|
–
|
|
|
13
|
Citadel Advisors
Miami,
Florida
|
$45.9M
|
-$23.8M
|
-547,348
|
-35%
|
|
|
14
|
Logos Global Management
San Francisco,
California
|
$45.4M
|
+$10.9M
|
+250,000
|
+33%
|
|
|
15
|
Lord, Abbett & Co
Jersey City,
New Jersey
|
$32M
|
+$38K
|
+874
|
+0.1%
|
|
|
16
|
Geode Capital Management
Boston,
Massachusetts
|
$30.1M
|
+$1.67M
|
+38,490
|
+6%
|
|
|
17
|
Avidity Partners Management
Dallas,
Texas
|
$25.5M
|
-$12.1M
|
-278,219
|
-33%
|
|
|
18
|
Vestal Point Capital
New York
|
$22M
|
-$10.4M
|
-240,000
|
-33%
|
|
|
19
|
Nationale-Nederlanden Powszechne Towarzystwo Emerytalne
Warszawa,
Poland
|
$21.4M
|
+$20.5M
|
+471,736
|
New
|
|
|
20
|
Point72 Asset Management
Stamford,
Connecticut
|
$18M
|
+$11.3M
|
+259,445
|
+190%
|
|
|
21
|
|
$14.3M
|
-$1.26M
|
-28,937
|
-8%
|
|
|
22
|
Northern Trust
Chicago,
Illinois
|
$12.1M
|
+$3.14M
|
+72,125
|
+37%
|
|
|
23
|
Charles Schwab
San Francisco,
California
|
$10.6M
|
+$6.82M
|
+156,675
|
+202%
|
|
|
24
|
Prosight Management
Dallas,
Texas
|
$9.31M
|
+$8.92M
|
+205,000
|
New
|
|
|
25
|
Alyeska Investment Group
Chicago,
Illinois
|
$9.23M
|
+$165K
|
+3,800
|
+2%
|
|
