|
1
|
RA Capital Management
Boston,
Massachusetts
|
$98.3M
|
–
|
–
|
–
|
|
|
2
|
Fidelity Investments
Boston,
Massachusetts
|
$50.1M
|
-$14.5M
|
-1,680,109
|
-26%
|
|
|
3
|
BVF Inc
San Francisco,
California
|
$49.1M
|
–
|
–
|
–
|
|
|
4
|
|
$35.6M
|
–
|
–
|
–
|
|
|
5
|
Citadel Advisors
Miami,
Florida
|
$33.5M
|
-$2.69M
|
-311,004
|
-9%
|
|
|
6
|
Janus Henderson Group
London,
|
$20.7M
|
-$1.18M
|
-135,991
|
-7%
|
|
|
7
|
|
$18.9M
|
+$1.06M
|
+122,522
|
+7%
|
|
|
8
|
Adage Capital Partners
Boston,
Massachusetts
|
$14.5M
|
+$1.78M
|
+205,475
|
+18%
|
|
|
9
|
Vanguard Group
Malvern,
Pennsylvania
|
$10.5M
|
+$322K
|
+37,202
|
+4%
|
|
|
10
|
Geode Capital Management
Boston,
Massachusetts
|
$4.38M
|
+$185K
|
+21,386
|
+6%
|
|
|
11
|
Samsara BioCapital
Palo Alto,
California
|
$3.87M
|
–
|
–
|
–
|
|
|
12
|
State Street
Boston,
Massachusetts
|
$3.73M
|
+$138K
|
+16,014
|
+5%
|
|
|
13
|
Northern Trust
Chicago,
Illinois
|
$2.19M
|
+$97.9K
|
+11,317
|
+6%
|
|
|
14
|
Alyeska Investment Group
Chicago,
Illinois
|
$2.12M
|
+$194K
|
+22,490
|
+13%
|
|
|
15
|
Nuveen
Charlotte,
North Carolina
|
$875K
|
+$129K
|
+14,872
|
+22%
|
|
|
16
|
Millennium Management
New York
|
$771K
|
-$249K
|
-28,756
|
-29%
|
|
|
17
|
|
$724K
|
+$406K
|
+46,992
|
+230%
|
|
|
18
|
|
$656K
|
+$437K
|
+50,521
|
+475%
|
|
|
19
|
|
$654K
|
+$527K
|
+60,933
|
New
|
|
|
20
|
Zacks Investment Management
Chicago,
Illinois
|
$631K
|
+$509K
|
+58,804
|
New
|
|
|
21
|
DekaBank Deutsche Girozentrale
Frankfurt,
Germany
|
$579K
|
–
|
–
|
–
|
|
|
22
|
Bank of New York Mellon
New York
|
$566K
|
-$2.62K
|
-303
|
-0.6%
|
|
|
23
|
Janney Montgomery Scott
Philadelphia,
Pennsylvania
|
$553K
|
+$446K
|
+51,548
|
New
|
|
|
24
|
Barclays
London,
United Kingdom
|
$512K
|
+$258K
|
+29,800
|
+166%
|
|
|
25
|
Charles Schwab
San Francisco,
California
|
$495K
|
-$22.6K
|
-2,609
|
-5%
|
|
