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Janux Therapeutics

190 hedge funds and large institutions have $828M invested in Janux Therapeutics in 2026 Q1 according to their latest regulatory filings, with 46 funds opening new positions, 66 increasing their positions, 54 reducing their positions, and 28 closing their positions.

New
Increased
Maintained
Reduced
Closed

64% more first-time investments, than exits

New positions opened: 46 | Existing positions closed: 28

22% more repeat investments, than reductions

Existing positions increased: 66 | Existing positions reduced: 54

8% more funds holding

Funds holding: 176190 (+14)

8% more call options, than puts

Call options by funds: $7.2M | Put options by funds: $6.69M

4% less capital invested

Capital invested by funds: $860M → $828M (-$32.1M)

5.47% less ownership

Funds ownership: 103.42%97.95% (-5.5%)

50% less funds holding in top 10

Funds holding in top 10: 21 (-1)

Holders
190
Holders Change
+14
Holders Change %
+7.95%
% of All Funds
2.34%
Holding in Top 10
1
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-50%
% of All Funds
0.01%
New
46
Increased
66
Reduced
54
Closed
28
Calls
$7.2M
Puts
$6.69M
Net Calls
+$505K
Net Calls Change
+$7.64M
Name Holding Trade Value Shares
Change
Change in
Stake
RCM
1
RA Capital Management
Massachusetts
$156M
BlackRock
2
BlackRock
New York
$75.5M +$18.6M +1,353,033 +33%
Janus Henderson Group
3
Janus Henderson Group
United Kingdom
$58.3M -$15.8M -1,154,044 -22%
PM
4
Prosight Management
Texas
$49.3M +$15.9M +1,157,477 +48%
Fidelity Investments
5
Fidelity Investments
Massachusetts
$35.2M -$13.4M -976,660 -28%
State Street
6
State Street
Massachusetts
$34.2M -$19.1M -1,389,934 -36%
VCM
7
Vanguard Capital Management
Pennsylvania
$25.2M +$24.8M +1,811,365 New
TCM
8
TCG Crossover Management
California
$24.9M
Alyeska Investment Group
9
Alyeska Investment Group
Illinois
$22.3M +$4.11M +300,000 +23%
Wellington Management Group
10
Wellington Management Group
Massachusetts
$22.2M -$172K -12,536 -0.8%
VPM
11
Vanguard Portfolio Management
Pennsylvania
$17.9M +$17.7M +1,290,256 New
DTC
12
Deep Track Capital
Connecticut
$16.5M +$15.1M +1,097,701 +1,225%
Point72 Asset Management
13
Point72 Asset Management
Connecticut
$16.1M +$2.66M +194,321 +20%
Geode Capital Management
14
Geode Capital Management
Massachusetts
$15.9M +$454K +33,142 +3%
Balyasny Asset Management
15
Balyasny Asset Management
Illinois
$15.2M +$2.81M +204,596 +23%
LGM
16
Logos Global Management
California
$13.9M
O
17
OrbiMed
New York
$13.7M -$13.3M -970,826 -50%
NCM
18
Nantahala Capital Management
Connecticut
$11.3M +$11.1M +809,914 New
Bank of America
19
Bank of America
North Carolina
$11.1M +$868K +63,316 +9%
ICM
20
Irenic Capital Management
New York
$10.6M +$10.5M +765,804 New
WP
21
Woodline Partners
California
$10.3M -$3.97M -289,189 -28%
Morgan Stanley
22
Morgan Stanley
New York
$9.78M +$1.17M +85,555 +14%
Squarepoint
23
Squarepoint
New York
$8.4M +$2.92M +213,048 +54%
Goldman Sachs
24
Goldman Sachs
New York
$8.37M -$6.47M -471,643 -44%
TCM
25
Tang Capital Management
California
$6.95M +$6.86M +500,000 New

JANX Hedge Fund Activity: Q1 2026 in Review

190 of the 8,126 institutional investors tracked by Wall St. Rank reported a position in Janux Therapeutics (JANX) for Q1 2026, worth a combined $828M — down 3.7% from $860M a quarter earlier.

Buyers outnumbered sellers: 46 funds opened new JANX positions and 28 closed out — a net gain of 18 holders — while 66 added to existing stakes and 54 trimmed.

The largest buyer was BlackRock, adding an estimated $18.6M. The largest seller was State Street, cutting an estimated $19.1M.

  • 190 institutional investors held Janux Therapeutics (JANX) as of Q1 2026, up from 176 in Q4 2025.
  • Funds reported $828M of Janux Therapeutics stock for Q1 2026, down 3.7% quarter-over-quarter.
  • 46 funds opened new Janux Therapeutics positions in Q1 2026 and 28 closed out, a net change of +18 holders.
  • The largest Janux Therapeutics buyer in Q1 2026 was BlackRock, an estimated $18.6M added.
  • The largest Janux Therapeutics seller in Q1 2026 was State Street, an estimated $19.1M sold.

Based on aggregated 13F filings for Q1 2026.