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Janux Therapeutics

174 hedge funds and large institutions have $1.59B invested in Janux Therapeutics in 2025 Q3 according to their latest regulatory filings, with 22 funds opening new positions, 57 increasing their positions, 64 reducing their positions, and 22 closing their positions.

New
Increased
Maintained
Reduced
Closed

172% more call options, than puts

Call options by funds: $14.6M | Put options by funds: $5.39M

5% more capital invested

Capital invested by funds: $1.51B → $1.59B (+$78.5M)

0% more funds holding

Funds holding: 174174 (0)

0% more first-time investments, than exits

New positions opened: 22 | Existing positions closed: 22

2.17% less ownership

Funds ownership: 110.61%108.44% (-2.2%)

11% less repeat investments, than reductions

Existing positions increased: 57 | Existing positions reduced: 64

40% less funds holding in top 10

Funds holding in top 10: 53 (-2)

Holders
174
Holders Change
Holders Change %
0%
% of All Funds
2.28%
Holding in Top 10
3
Holding in Top 10 Change
-2
Holding in Top 10 Change %
-40%
% of All Funds
0.04%
New
22
Increased
57
Reduced
64
Closed
22
Calls
$14.6M
Puts
$5.39M
Net Calls
+$9.26M
Net Calls Change
+$4.19M
Name Holding Trade Value Shares
Change
Change in
Stake
RCM
1
RA Capital Management
Massachusetts
$273M
Fidelity Investments
2
Fidelity Investments
Massachusetts
$221M +$4.07M +167,320 +2%
Janus Henderson Group
3
Janus Henderson Group
United Kingdom
$115M +$5.86M +240,780 +5%
BlackRock
4
BlackRock
New York
$91.2M +$7.99M +328,147 +10%
PBA
5
Paradigm Biocapital Advisors
New York
$71.4M
Adage Capital Partners
6
Adage Capital Partners
Massachusetts
$67.8M +$6.09M +250,000 +10%
Vanguard Group
7
Vanguard Group
Pennsylvania
$59.1M +$5.54M +227,676 +10%
State Street
8
State Street
Massachusetts
$46.2M +$12.3M +503,357 +36%
O
9
OrbiMed
New York
$43.2M +$13.5M +555,800 +46%
Point72 Asset Management
10
Point72 Asset Management
Connecticut
$41.8M -$10.6M -433,700 -20%
T. Rowe Price Associates
11
T. Rowe Price Associates
Maryland
$30.9M -$12.9M -527,871 -29%
Geode Capital Management
12
Geode Capital Management
Massachusetts
$26.5M +$4.42M +181,552 +20%
WP
13
Woodline Partners
California
$25.1M -$5.24M -215,000 -17%
T. Rowe Price Investment Management
14
T. Rowe Price Investment Management
Maryland
$23.8M +$23.7M +972,691 New
RAM
15
Readystate Asset Management
Illinois
$23.5M +$6.44M +264,423 +38%
LGM
16
Logos Global Management
California
$22.9M -$1.58M -65,000 -7%
Franklin Resources
17
Franklin Resources
California
$21.7M -$4.42M -181,440 -17%
PM
18
Prosight Management
Texas
$21.1M +$279K +11,446 +1%
CAM
19
Cormorant Asset Management
Massachusetts
$20.8M -$15.8M -650,000 -43%
Citadel Advisors
20
Citadel Advisors
Florida
$19.6M -$10.4M -428,342 -35%
Wellington Management Group
21
Wellington Management Group
Massachusetts
$17.1M +$5.1M +209,243 +42%
TCM
22
Tang Capital Management
California
$17.1M +$12.2M +500,000 +250%
Goldman Sachs
23
Goldman Sachs
New York
$16M +$7.47M +306,618 +88%
FTM
24
First Turn Management
California
$15.6M +$4.68M +192,279 +43%
MB
25
MPM BioImpact
Massachusetts
$15M

JANX Hedge Fund Activity: Q3 2025 in Review

174 of the 7,620 institutional investors tracked by Wall St. Rank reported a position in Janux Therapeutics (JANX) for Q3 2025, worth a combined $1.59B — up 5.2% from $1.51B a quarter earlier.

Fund positioning in JANX was balanced in Q3 2025: 22 funds opened new positions, 22 closed out, 57 added to existing stakes and 64 trimmed.

The largest buyer was T. Rowe Price Investment Management, opening a new position worth an estimated $23.7M. The largest seller was EcoR1 Capital, exiting entirely with an estimated $34M sold.

  • 174 institutional investors held Janux Therapeutics (JANX) as of Q3 2025, unchanged from Q2 2025.
  • Funds reported $1.59B of Janux Therapeutics stock for Q3 2025, up 5.2% quarter-over-quarter.
  • 22 funds opened new Janux Therapeutics positions in Q3 2025 and 22 closed out, a net change of 0 holders.
  • The largest Janux Therapeutics buyer in Q3 2025 was T. Rowe Price Investment Management, an estimated $23.7M added.
  • The largest Janux Therapeutics seller in Q3 2025 was EcoR1 Capital, an estimated $34M sold.

Based on aggregated 13F filings for Q3 2025.