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Janux Therapeutics

174 hedge funds and large institutions have $1.51B invested in Janux Therapeutics in 2025 Q2 according to their latest regulatory filings, with 16 funds opening new positions, 80 increasing their positions, 54 reducing their positions, and 22 closing their positions.

New
Increased
Maintained
Reduced
Closed

48% more repeat investments, than reductions

Existing positions increased: 80 | Existing positions reduced: 54

34% more call options, than puts

Call options by funds: $20.2M | Put options by funds: $15.1M

1.86% less ownership

Funds ownership: 112.47%110.61% (-1.9%)

4% less funds holding

Funds holding: 181174 (-7)

16% less capital invested

Capital invested by funds: $1.81B → $1.51B (-$292M)

27% less first-time investments, than exits

New positions opened: 16 | Existing positions closed: 22

29% less funds holding in top 10

Funds holding in top 10: 75 (-2)

Holders
174
Holders Change
-7
Holders Change %
-3.87%
% of All Funds
2.29%
Holding in Top 10
5
Holding in Top 10 Change
-2
Holding in Top 10 Change %
-28.57%
% of All Funds
0.07%
New
16
Increased
80
Reduced
54
Closed
22
Calls
$20.2M
Puts
$15.1M
Net Calls
+$5.07M
Net Calls Change
-$7.75M
Name Holding Trade Value Shares
Change
Change in
Stake
RCM
1
RA Capital Management
Massachusetts
$258M
Fidelity Investments
2
Fidelity Investments
Massachusetts
$205M +$123K +4,670 +0.1%
Janus Henderson Group
3
Janus Henderson Group
United Kingdom
$103M -$3.63M -137,760 -3%
BlackRock
4
BlackRock
New York
$78.6M +$14M +529,888 +18%
PBA
5
Paradigm Biocapital Advisors
New York
$67.5M -$10.8M -409,651 -12%
Adage Capital Partners
6
Adage Capital Partners
Massachusetts
$58.3M -$29.8M -1,129,574 -31%
Vanguard Group
7
Vanguard Group
Pennsylvania
$50.6M -$2.35M -89,232 -4%
Point72 Asset Management
8
Point72 Asset Management
Connecticut
$49.5M +$46.6M +1,767,238 +469%
T. Rowe Price Associates
9
T. Rowe Price Associates
Maryland
$41.4M +$10.6M +400,601 +29%
CAM
10
Cormorant Asset Management
Massachusetts
$34.6M -$13.2M -500,000 -25%
EC
11
EcoR1 Capital
California
$34M
State Street
12
State Street
Massachusetts
$32.1M +$438K +16,611 +1%
WP
13
Woodline Partners
California
$28.7M -$5.67M -215,157 -15%
Citadel Advisors
14
Citadel Advisors
Florida
$28.4M +$13.8M +524,462 +74%
O
15
OrbiMed
New York
$28M +$11.9M +451,734 +60%
Franklin Resources
16
Franklin Resources
California
$24.7M -$3.09M -117,284 -10%
LGM
17
Logos Global Management
California
$23.1M -$17.1M -650,000 -39%
Geode Capital Management
18
Geode Capital Management
Massachusetts
$20.8M +$3.2M +121,403 +16%
Bank of America
19
Bank of America
North Carolina
$19.9M +$2.9M +110,097 +15%
PM
20
Prosight Management
Texas
$19.7M +$4.32M +164,003 +24%
RAM
21
Readystate Asset Management
Illinois
$16.1M +$11.1M +419,396 +152%
Pictet Asset Management
22
Pictet Asset Management
Switzerland
$15.5M +$392K +14,880 +2%
MB
23
MPM BioImpact
Massachusetts
$14.2M +$1.24M +47,089 +8%
Wellington Management Group
24
Wellington Management Group
Massachusetts
$11.4M +$2.61M +98,884 +25%
CM
25
Caption Management
Oklahoma
$10.6M +$10.9M +412,569 +928%

JANX Hedge Fund Activity: Q2 2025 in Review

174 of the 7,595 institutional investors tracked by Wall St. Rank reported a position in Janux Therapeutics (JANX) for Q2 2025, worth a combined $1.51B — down 16% from $1.81B a quarter earlier.

Sellers outnumbered buyers: 22 funds closed out of JANX and 16 opened new positions — a net loss of 6 holders — while 54 trimmed existing stakes and 80 added.

The largest buyer was Point72 Asset Management, adding an estimated $46.6M. The largest seller was Adage Capital Partners, cutting an estimated $29.8M.

  • 174 institutional investors held Janux Therapeutics (JANX) as of Q2 2025, down from 181 in Q1 2025.
  • Funds reported $1.51B of Janux Therapeutics stock for Q2 2025, down 16% quarter-over-quarter.
  • 16 funds opened new Janux Therapeutics positions in Q2 2025 and 22 closed out, a net change of -6 holders.
  • The largest Janux Therapeutics buyer in Q2 2025 was Point72 Asset Management, an estimated $46.6M added.
  • The largest Janux Therapeutics seller in Q2 2025 was Adage Capital Partners, an estimated $29.8M sold.

Based on aggregated 13F filings for Q2 2025.