Squarepoint
SEPN

Squarepoint’s Septerna Inc SEPN Stock Holding History

Squarepoint’s Portfolio SEPN Stock Details SEPN Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q2 		$711K Buy
21,219
+3,136
+17% +$89K ﹤0.01% 3160
2026
Q1 		$435K Buy
18,083
+3,236
+22% +$85.1K ﹤0.01% 3413
2025
Q4 		$414K Buy
+14,847
New +$355K ﹤0.01% 3357
2025
Q3 		– Sell
-10,737
Closed -$113K – 5132
2025
Q2 		$113K Buy
+10,737
New +$88.4K ﹤0.01% 4139

Other funds holding SEPN

RCM
RA Capital Management Boston, Massachusetts $11.5B AUM 168.77% 1-Year Est. Return
TGV
TRV GP V Boston, Massachusetts $498M AUM 267.53% 1-Year Est. Return
DCM
Driehaus Capital Management Chicago, Illinois $17.3B AUM 211.34% 1-Year Est. Return
TGV
TRV GP VI Boston, Massachusetts $232M AUM 247.08% 1-Year Est. Return
SB
Samsara BioCapital Palo Alto, California $1.22B AUM 242.83% 1-Year Est. Return
Goldman Sachs
Goldman Sachs New York $1.15T AUM 47.82% 1-Year Est. Return
BlackRock
BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return
SL
Siren LLC Greenwich, Connecticut $4.94B AUM 244.43% 1-Year Est. Return
ACA
Avoro Capital Advisors New York $11.1B AUM 207.82% 1-Year Est. Return
JT
Jupiter Topco New York $245B AUM

Squarepoint's SEPN Position: Q2 2026 in Review

Squarepoint increased its Septerna Inc (SEPN) stake by 17% in Q2 2026, buying an estimated $89K and bringing the position to 21,219 shares worth $711K. The position accounts for ﹤0.01% of the portfolio, ranked #3160.

Squarepoint first reported a position in SEPN in Q2 2025 and has held it in 4 quarters since. 154 funds tracked by Wall St. Rank hold SEPN as of Q2 2026.

  • Squarepoint held 21,219 shares of Septerna Inc worth $711K as of Q2 2026.
  • Squarepoint bought 3,136 Septerna Inc shares in Q2 2026, an estimated $89K.
  • Septerna Inc made up ﹤0.01% of Squarepoint's portfolio in Q2 2026, its #3160 holding.
  • Squarepoint first reported a position in Septerna Inc in Q2 2025 and has held it in 4 quarters since.
  • 154 funds tracked by Wall St. Rank held Septerna Inc as of Q2 2026.

Based on Squarepoint's 13F filing for Q2 2026, filed 14 Aug 2026.