Squarepoint
SEPN

Squarepoint’s Septerna Inc SEPN Stock Holding History

Squarepoint’s Portfolio SEPN Stock Details SEPN Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$435K Buy
18,083
+3,236
+22% +$85.1K ﹤0.01% 3413
2025
Q4 		$414K Buy
+14,847
New +$355K ﹤0.01% 3357
2025
Q3 		– Sell
-10,737
Closed -$113K – 5132
2025
Q2 		$113K Buy
+10,737
New +$88.4K ﹤0.01% 4139

Other funds holding SEPN

RCM
RA Capital Management Boston, Massachusetts $9.44B AUM 157.3% 1-Year Est. Return
TGV
TRV GP V Boston, Massachusetts $401M AUM 284.76% 1-Year Est. Return
DCM
Driehaus Capital Management Chicago, Illinois $13.6B AUM 173.98% 1-Year Est. Return
TGV
TRV GP VI Boston, Massachusetts $136M AUM 328.39% 1-Year Est. Return
SB
Samsara BioCapital Palo Alto, California $1.03B AUM 214.94% 1-Year Est. Return
Goldman Sachs
Goldman Sachs New York $871B AUM 31.28% 1-Year Est. Return
SL
Siren LLC Greenwich, Connecticut $3.61B AUM 203.3% 1-Year Est. Return
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
BI
BVF Inc San Francisco, California $3.14B AUM 249.53% 1-Year Est. Return
ACA
Avoro Capital Advisors New York $10.2B AUM 149.19% 1-Year Est. Return

Squarepoint's SEPN Position: Q1 2026 in Review

Squarepoint increased its Septerna Inc (SEPN) stake by 22% in Q1 2026, buying an estimated $85.1K and bringing the position to 18,083 shares worth $435K. The position accounts for ﹤0.01% of the portfolio, ranked #3413.

Squarepoint first reported a position in SEPN in Q2 2025 and has held it in 3 quarters since. 124 funds tracked by Wall St. Rank hold SEPN as of Q1 2026.

  • Squarepoint held 18,083 shares of Septerna Inc worth $435K as of Q1 2026.
  • Squarepoint bought 3,236 Septerna Inc shares in Q1 2026, an estimated $85.1K.
  • Septerna Inc made up ﹤0.01% of Squarepoint's portfolio in Q1 2026, its #3413 holding.
  • Squarepoint first reported a position in Septerna Inc in Q2 2025 and has held it in 3 quarters since.
  • 124 funds tracked by Wall St. Rank held Septerna Inc as of Q1 2026.

Based on Squarepoint's 13F filing for Q1 2026, filed 15 May 2026.