Simplex Trading
SEPN

Simplex Trading’s Septerna Inc SEPN Stock Holding History

Simplex Trading’s Portfolio SEPN Stock Details SEPN Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$57.7K Buy
2,400
+1,100
+85% +$28.9K ﹤0.01% 5718
2025
Q4 		$36.2K Sell
1,300
-1,600
-55% -$38.2K ﹤0.01% 5938
2025
Q3 		$54K Buy
2,900
+1,100
+61% +$14.4K ﹤0.01% 6385
2025
Q2 		$19K Buy
1,800
+400
+29% +$3.29K ﹤0.01% 6827
2025
Q1 		$8K Buy
+1,400
New +$16K ﹤0.01% 7279

Other funds holding SEPN

RCM
RA Capital Management Boston, Massachusetts $9.44B AUM 157.3% 1-Year Est. Return
TGV
TRV GP V Boston, Massachusetts $401M AUM 284.76% 1-Year Est. Return
DCM
Driehaus Capital Management Chicago, Illinois $13.6B AUM 173.98% 1-Year Est. Return
TGV
TRV GP VI Boston, Massachusetts $136M AUM 328.39% 1-Year Est. Return
SB
Samsara BioCapital Palo Alto, California $1.03B AUM 214.94% 1-Year Est. Return
Goldman Sachs
Goldman Sachs New York $871B AUM 31.28% 1-Year Est. Return
SL
Siren LLC Greenwich, Connecticut $3.61B AUM 203.3% 1-Year Est. Return
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
BI
BVF Inc San Francisco, California $3.14B AUM 249.53% 1-Year Est. Return
ACA
Avoro Capital Advisors New York $10.2B AUM 149.19% 1-Year Est. Return

Simplex Trading's SEPN Position: Q3 2025 in Review

Simplex Trading sold out of Septerna Inc (SEPN) in Q3 2025, closing a stake of 23,525 shares — an estimated $309K sold.

Simplex Trading first reported a position in SEPN in Q1 2025 and held it in 2 quarters. The position peaked at $248K in Q2 2025. 82 funds tracked by Wall St. Rank hold SEPN as of Q3 2025.

  • Simplex Trading reported no remaining Septerna Inc position as of Q3 2025 after selling out during the quarter.
  • Simplex Trading sold 23,525 Septerna Inc shares in Q3 2025, an estimated $309K.
  • Simplex Trading first reported a position in Septerna Inc in Q1 2025 and held it in 2 quarters.
  • Simplex Trading's Septerna Inc position peaked at $248K in Q2 2025.
  • 82 funds tracked by Wall St. Rank held Septerna Inc as of Q3 2025.

Based on Simplex Trading's 13F filing for Q3 2025, filed 12 Nov 2025.