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SPDR S&P Biotech ETF
XBI

Overview Fund Activity

613 hedge funds and large institutions have $9.73B invested in SPDR S&P Biotech ETF in 2025 Q2 according to their latest regulatory filings, with 54 funds opening new positions, 159 increasing their positions, 270 reducing their positions, and 102 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
613
Holders Change
-59
Holders Change %
-8.78%
% of All Funds
8.22%
Holding in Top 10
15
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.2%
New
54
Increased
159
Reduced
270
Closed
102
Calls
$1.47B
Puts
$2.24B
Net Calls
-$777M
Net Calls Change
+$309M

Top Buyers

1
Goldman Sachs
Goldman Sachs
New York
$1.5B
2
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
Ontario, Canada
$1.01B
3
Citigroup
Citigroup
New York
$1.06B
4
Wells Fargo
Wells Fargo
California
$243M
5
JFG
Jefferies Financial Group
New York
$119M

Top Sellers

1
DFG
Demars Financial Group
Washington
$247K
2
UBS Group
UBS Group
Switzerland
$341M
3
BNP Paribas Financial Markets
BNP Paribas Financial Markets
France
$631M
4
HIIFS
Harel Insurance Investments & Financial Services
Israel
$0
5
Squarepoint
Squarepoint
New York
$39.2M
Name Holding Trade Value Shares
Change 		Shares
Change %
PA
151
Parallel Advisors
California
$2.08M -$191K -2,298 -8%
MML Investors Services
152
MML Investors Services
Massachusetts
$2.07M -$107K -1,285 -5%
EFS
153
Econ Financial Services
Pennsylvania
$2.02M -$88.5K -1,067 -4%
RIA
154
RPG Investment Advisory
California
$2.01M -$2.19M -26,461 -52%
HCP
155
Holt Capital Partners
Texas
$1.99M -$222K -2,680 -10%
HCMT
156
Highland Capital Management (Tennessee)
Tennessee
$1.97M -$98.6K -1,189 -5%
AMG
157
Asset Management Group
Connecticut
$1.96M +$166 +2 +0%
P
158
&Partners
Tennessee
$1.95M +$441K +5,323 +29%
EH
159
Equitable Holdings
New York
$1.88M -$58.1K -700 -3%
Qube Research & Technologies (QRT)
160
Qube Research & Technologies (QRT)
United Kingdom
$1.87M -$7.33M -88,367 -80%
CWM
161
Congress Wealth Management
Massachusetts
$1.87M +$41.1K +496 +2%
SG
162
StoneX Group
New York
$1.85M -$178K -2,151 -9%
KAS
163
Kestra Advisory Services
Texas
$1.84M -$5.72K -69 -0.3%
SCM
164
SOL Capital Management
Maryland
$1.82M -$668K -8,052 -27%
PPW
165
Parcion Private Wealth
Washington
$1.82M – – –
BS
166
Banco Santander
Spain
$1.81M +$177K +2,136 +11%
SCM
167
SCS Capital Management
Massachusetts
$1.79M -$82.8K -999 -4%
MWM
168
Modera Wealth Management
New Jersey
$1.77M -$115K -1,384 -6%
SCM
169
Sage Capital Management
New Jersey
$1.77M -$16.2K -195 -0.9%
HBWM
170
Hollow Brook Wealth Management
New York
$1.74M +$53.7K +648 +3%
ECM
171
Eisler Capital Management
United Kingdom
$1.72M -$509K -6,141 -23%
BPA
172
Beacon Pointe Advisors
California
$1.72M -$166K -2,000 -9%
AWM
173
AE Wealth Management
Kansas
$1.71M +$94.6K +1,141 +6%
GEA
174
Glen Eagle Advisors
New Jersey
$1.69M -$42.7K -515 -2%
FLPIM
175
F.L. Putnam Investment Management
Massachusetts
$1.69M -$167K -2,013 -9%
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