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State Street SPDR S&P Biotech ETF

813 hedge funds and large institutions have $16.7B invested in State Street SPDR S&P Biotech ETF in 2026 Q1 according to their latest regulatory filings, with 107 funds opening new positions, 251 increasing their positions, 240 reducing their positions, and 94 closing their positions.

New
Increased
Maintained
Reduced
Closed

19.17% more ownership

Funds ownership: 199.2%218.37% (+19%)

16% more funds holding in top 10

Funds holding in top 10: 1922 (+3)

14% more first-time investments, than exits

New positions opened: 107 | Existing positions closed: 94

5% more repeat investments, than reductions

Existing positions increased: 251 | Existing positions reduced: 240

1% more capital invested

Capital invested by funds: $16.5B → $16.7B (+$196M)

0% more funds holding

Funds holding: 812813 (+1)

54% less call options, than puts

Call options by funds: $2.19B | Put options by funds: $4.74B

Holders
813
Holders Change
+1
Holders Change %
+0.12%
% of All Funds
10.01%
Holding in Top 10
22
Holding in Top 10 Change
+3
Holding in Top 10 Change %
+15.79%
% of All Funds
0.27%
New
107
Increased
251
Reduced
240
Closed
94
Calls
$2.19B
Puts
$4.74B
Net Calls
-$2.55B
Net Calls Change
+$758M
Name Holding Trade Value Shares
Change
Change in
Stake
BNP Paribas Financial Markets
1
BNP Paribas Financial Markets
France
$2.7B +$570M +4,568,518 +28%
Bank of America
2
Bank of America
North Carolina
$1.85B +$212M +1,700,851 +13%
Goldman Sachs
3
Goldman Sachs
New York
$1.75B -$771M -6,177,074 -31%
Morgan Stanley
4
Morgan Stanley
New York
$1.58B +$105M +839,870 +7%
Citigroup
5
Citigroup
New York
$1.36B -$233M -1,863,806 -15%
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
6
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
Ontario, Canada
$1.24B -$355M -2,847,000 -23%
JP Morgan Chase
7
JP Morgan Chase
New York
$740M +$370M +2,965,686 +91%
UBS Group
8
UBS Group
Switzerland
$453M +$71.1M +569,529 +19%
Barclays
9
Barclays
United Kingdom
$362M +$118M +943,752 +50%
Wells Fargo
10
Wells Fargo
California
$351M -$102M -820,056 -23%
JFG
11
Jefferies Financial Group
New York
$296M +$74.9M +599,631 +35%
Bessemer Group
12
Bessemer Group
New Jersey
$231M -$5.94M -47,602 -3%
Canada Pension Plan Investment Board
13
Canada Pension Plan Investment Board
Ontario, Canada
$225M
D.E. Shaw & Co
14
D.E. Shaw & Co
New York
$175M +$78.6M +630,015 +85%
Bank of Montreal
15
Bank of Montreal
Ontario, Canada
$107M +$83.9M +672,007 +413%
MIH
16
Meitav Investment House
Israel
$103M -$20M -159,840 -16%
Ameriprise
17
Ameriprise
Minnesota
$102M +$15.4M +123,269 +18%
LPL Financial
18
LPL Financial
California
$101M -$10.4M -83,001 -9%
HSBC Holdings
19
HSBC Holdings
United Kingdom
$92.6M +$10.9M +87,009 +14%
ERSOT
20
Employees Retirement System of Texas
Texas
$87.9M -$4.62M -37,000 -5%
GF
21
Greenhouse Funds
Maryland
$83.1M -$4.57M -36,575 -5%
AssetMark Inc
22
AssetMark Inc
California
$79.6M -$1.6M -12,828 -2%
MSR
23
Main Street Research
Connecticut
$72.5M +$25.8M +206,953 +57%
Royal Bank of Canada
24
Royal Bank of Canada
Ontario, Canada
$65.2M +$2.3M +18,452 +4%
N
25
Natixis
France
$62.4M -$530K -4,245 -0.9%