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SPDR S&P Biotech ETF
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Overview Fund Activity

731 hedge funds and large institutions have $9.85B invested in SPDR S&P Biotech ETF in 2024 Q4 according to their latest regulatory filings, with 101 funds opening new positions, 193 increasing their positions, 280 reducing their positions, and 115 closing their positions.

Holders
731
Holders Change
-32
Holders Change %
-4.19%
% of All Funds
9.74%
Holding in Top 10
16
Holding in Top 10 Change
-5
Holding in Top 10 Change %
-23.81%
% of All Funds
0.21%
New
101
Increased
193
Reduced
280
Closed
115
Calls
$2.07B
Puts
$3.32B
Net Calls
-$1.26B
Net Calls Change
-$729M

Top Buyers

1
BNP Paribas Financial Markets
1
BNP Paribas Financial Markets
France
$1.07B
2
Citigroup
2
Citigroup
New York
$1B
3
Bank of America
3
Bank of America
North Carolina
$767M
4
Morgan Stanley
4
Morgan Stanley
New York
$916M
5
UBS Group
5
UBS Group
Switzerland
$322M

Top Sellers

1
JPMorgan Chase & Co
1
JPMorgan Chase & Co
New York
$721M
2
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
2
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
Ontario, Canada
$465M
3
Goldman Sachs
3
Goldman Sachs
New York
$861M
4
CI Investments Inc
4
CI Investments Inc
Ontario, Canada
$6.66M
5
CI
5
Clal Insurance
Israel
$48.1M
Name Market Value Shares Shares
Change 		Shares
Change %
BNP Paribas Financial Markets
1
BNP Paribas Financial Markets
France
$1.07B 11,884,490 +8,873,467 +295%
Citigroup
2
Citigroup
New York
$1B 11,151,595 +3,401,781 +44%
Morgan Stanley
3
Morgan Stanley
New York
$916M 10,170,065 +2,150,123 +27%
Goldman Sachs
4
Goldman Sachs
New York
$861M 9,555,029 -3,185,665 -25%
Bank of America
5
Bank of America
North Carolina
$767M 8,518,061 +2,185,085 +35%
JPMorgan Chase & Co
6
JPMorgan Chase & Co
New York
$721M 8,008,848 -4,266,737 -35%
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
7
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
Ontario, Canada
$465M 5,165,000 -4,064,000 -44%
UBS Group
8
UBS Group
Switzerland
$322M 3,578,542 +1,819,814 +103%
Wells Fargo
9
Wells Fargo
California
$198M 2,196,261 +189,004 +9%
Canada Pension Plan Investment Board
10
Canada Pension Plan Investment Board
Ontario, Canada
$158M 1,758,000 – –
BCM
11
BlueCrest Capital Management
Jersey
$138M 1,532,882 +1,532,882 New
MASUI
12
MIRAE ASSET SECURITIES (USA) INC.
New York
$135M 1,500,000 +600,000 +67%
Bessemer Group
13
Bessemer Group
New Jersey
$124M 1,376,834 +73,866 +6%
Jane Street
14
Jane Street
New York
$119M 1,315,816 +371,088 +39%
RCM
15
RA Capital Management
Massachusetts
$111M 1,228,240 +1,228,240 New
HSBC Holdings
16
HSBC Holdings
United Kingdom
$98.3M 1,092,063 +325,066 +42%
Citadel Advisors
17
Citadel Advisors
Florida
$82.5M 916,400 +343,327 +60%
ERSOT
18
Employees Retirement System of Texas
Texas
$79M 877,272 +220,400 +34%
Ameriprise
19
Ameriprise
Minnesota
$67.6M 751,090 -96,730 -11%
Northwestern Mutual Wealth Management
20
Northwestern Mutual Wealth Management
Wisconsin
$63M 699,327 -391,610 -36%
LPL Financial
21
LPL Financial
California
$57.8M 641,784 -49,593 -7%
Raymond James Financial
22
Raymond James Financial
Florida
$55.5M 616,573 +616,573 New
JFG
23
Jefferies Financial Group
New York
$55M 610,733 +541,290 +779%
Squarepoint
24
Squarepoint
New York
$53.3M 592,350 +592,350 New
PF
25
Phoenix Financial
Israel
$52.4M 582,089 -112,600 -16%
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