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SPDR S&P Biotech ETF
XBI

Overview Fund Activity

700 hedge funds and large institutions have $6.42B invested in SPDR S&P Biotech ETF in 2022 Q3 according to their latest regulatory filings, with 100 funds opening new positions, 218 increasing their positions, 223 reducing their positions, and 93 closing their positions.

Holders
700
Holders Change
-2
Holders Change %
-0.28%
% of All Funds
12.11%
Holding in Top 10
33
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+3.13%
% of All Funds
0.57%
New
100
Increased
218
Reduced
223
Closed
93
Calls
$1.99B
Puts
$1.9B
Net Calls
+$89M
Net Calls Change
+$62.3M

Top Buyers

1
JPMorgan Chase & Co
1
JPMorgan Chase & Co
New York
$201M
2
Two Sigma Advisers
2
Two Sigma Advisers
New York
$105M
3
Janus Henderson Group
3
Janus Henderson Group
United Kingdom
$79.2M
4
Brown Advisory
4
Brown Advisory
Maryland
$77M
5
Two Sigma Investments
5
Two Sigma Investments
New York
$52.6M

Top Sellers

1
BNP Paribas Financial Markets
1
BNP Paribas Financial Markets
France
$165M
2
Goldman Sachs
2
Goldman Sachs
New York
$398M
3
UBS Group
3
UBS Group
Switzerland
$212M
4
Toronto Dominion Bank
4
Toronto Dominion Bank
Ontario, Canada
$144M
5
CI
5
Clal Insurance
Israel
$125M
Name Market Value Shares Shares
Change 		Shares
Change %
Morgan Stanley
1
Morgan Stanley
New York
$691M 8,714,161 -737,929 -8%
Bank of America
2
Bank of America
North Carolina
$688M 8,670,509 -654,073 -7%
Goldman Sachs
3
Goldman Sachs
New York
$398M 5,019,739 -1,578,160 -24%
Citigroup
4
Citigroup
New York
$390M 4,921,234 -129,263 -3%
UBS Group
5
UBS Group
Switzerland
$212M 2,668,373 -1,392,815 -34%
JPMorgan Chase & Co
6
JPMorgan Chase & Co
New York
$201M 2,536,595 +1,822,559 +255%
BNP Paribas Financial Markets
7
BNP Paribas Financial Markets
France
$165M 2,084,282 -1,691,513 -45%
Toronto Dominion Bank
8
Toronto Dominion Bank
Ontario, Canada
$144M 1,818,885 -1,275,000 -41%
CI
9
Clal Insurance
Israel
$125M 1,580,000 -862,000 -35%
APM
10
Avidity Partners Management
Texas
$117M 1,480,000 -395,000 -21%
Barclays
11
Barclays
United Kingdom
$110M 1,383,583 +434,845 +46%
Two Sigma Advisers
12
Two Sigma Advisers
New York
$105M 1,329,800 +1,329,800 New
HIIFS
13
Harel Insurance Investments & Financial Services
Israel
$95.2M 1,200,274 – –
Canada Pension Plan Investment Board
14
Canada Pension Plan Investment Board
Ontario, Canada
$95.2M 1,200,000 – –
Janus Henderson Group
15
Janus Henderson Group
United Kingdom
$79.2M 998,180 +998,180 New
HSBC Holdings
16
HSBC Holdings
United Kingdom
$78.8M 974,275 +234,186 +32%
Wells Fargo
17
Wells Fargo
California
$77.2M 972,990 +212,475 +28%
Brown Advisory
18
Brown Advisory
Maryland
$77M 970,255 +889,912 +1,108%
PF
19
Phoenix Financial
Israel
$70.6M 895,065 -23,782 -3%
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
20
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
Ontario, Canada
$61.1M 770,000 – –
LP
21
LMR Partners
United Kingdom
$59.4M 749,409 -184,394 -20%
LPL Financial
22
LPL Financial
California
$57.8M 728,939 +24,899 +4%
Two Sigma Investments
23
Two Sigma Investments
New York
$52.6M 663,400 +663,400 New
Royal Bank of Canada
24
Royal Bank of Canada
Ontario, Canada
$51.9M 654,748 +134,852 +26%
Millennium Management
25
Millennium Management
New York
$51M 643,160 +406,618 +172%
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