Two Sigma Advisers
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Two Sigma Advisers’s State Street SPDR S&P Biotech ETF XBI Stock Holding History

Two Sigma Advisers’s Portfolio XBI Stock Details XBI Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2024
Q4 		– Sell
-187,900
Closed -$18.6M – 2561
2024
Q3 		$18.6M Sell
187,900
-780,400
-81% -$76.7M 0.04% 336
2024
Q2 		$89.8M Buy
968,300
+362,300
+60% +$32.5M 0.2% 100
2024
Q1 		$57.5M Buy
606,000
+334,900
+124% +$31.1M 0.13% 159
2023
Q4 		$24.2M Sell
271,100
-65,400
-19% -$4.86M 0.06% 293
2023
Q3 		$24.6M Buy
336,500
+306,100
+1,007% +$24.5M 0.06% 264
2023
Q2 		$2.53M Sell
30,400
-1,711,500
-98% -$143M 0.01% 1073
2023
Q1 		$133M Buy
1,741,900
+788,700
+83% +$65.4M 0.34% 70
2022
Q4 		$79.1M Sell
953,200
-376,600
-28% -$30.5M 0.22% 99
2022
Q3 		$105M Buy
+1,329,800
New +$112M 0.31% 81
2022
Q2 		– Sell
-201,000
Closed -$18.1M – 2895
2022
Q1 		$18.1M Sell
201,000
-330,600
-62% -$30.5M 0.05% 345
2021
Q4 		$59.5M Buy
+531,600
New +$64.1M 0.15% 138
2021
Q2 		– Sell
-88,100
Closed -$12M – 2725
2021
Q1 		$12M Buy
+88,100
New +$13.2M 0.03% 511
2020
Q3 		– Sell
-82,000
Closed -$9.18M – 2654
2020
Q2 		$9.18M Sell
82,000
-374,600
-82% -$36.9M 0.03% 585
2020
Q1 		$35.4M Sell
456,600
-392,500
-46% -$34.8M 0.14% 174
2019
Q4 		$80.8M Buy
849,100
+327,200
+63% +$28.3M 0.19% 128
2019
Q3 		$39.8M Sell
521,900
-521,400
-50% -$43.3M 0.1% 240
2019
Q2 		$91.5M Buy
1,043,300
+743,500
+248% +$63.4M 0.23% 117
2019
Q1 		$27.1M Buy
299,800
+296,600
+9,269% +$25.2M 0.07% 334
2018
Q4 		$230K Buy
+3,200
New +$258K ﹤0.01% 2083

Other funds holding XBI

BNP Paribas Financial Markets
BNP Paribas Financial Markets Paris, France $289B AUM 60.46% 1-Year Est. Return
Citigroup
Citigroup New York $303B AUM 53.02% 1-Year Est. Return
Morgan Stanley
Morgan Stanley New York $1.89T AUM 35.08% 1-Year Est. Return
Goldman Sachs
Goldman Sachs New York $1.15T AUM 47.82% 1-Year Est. Return
Bank of America
Bank of America Charlotte, North Carolina $1.55T AUM 33.47% 1-Year Est. Return
JP Morgan Chase
JP Morgan Chase New York $1.81T AUM 41.13% 1-Year Est. Return
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund Toronto, Ontario, Canada $71.2B AUM 48.86% 1-Year Est. Return
UBS Group
UBS Group Zurich, Switzerland $786B AUM 40.34% 1-Year Est. Return
Wells Fargo
Wells Fargo San Francisco, California $617B AUM 30.33% 1-Year Est. Return
Canada Pension Plan Investment Board
Canada Pension Plan Investment Board Toronto Ontario, Ontario, Canada $181B AUM 41.77% 1-Year Est. Return

Two Sigma Advisers's XBI Position: Q4 2024 in Review

Two Sigma Advisers sold out of State Street SPDR S&P Biotech ETF (XBI) in Q4 2024, closing a stake of 187,900 shares — an estimated $18.6M sold.

Two Sigma Advisers first reported a position in XBI in Q4 2018 and held it in 19 quarters. The position peaked at $133M in Q1 2023. 738 funds tracked by Wall St. Rank hold XBI as of Q4 2024.

  • Two Sigma Advisers reported no remaining State Street SPDR S&P Biotech ETF position as of Q4 2024 after selling out during the quarter.
  • Two Sigma Advisers sold 187,900 State Street SPDR S&P Biotech ETF shares in Q4 2024, an estimated $18.6M.
  • Two Sigma Advisers first reported a position in State Street SPDR S&P Biotech ETF in Q4 2018 and held it in 19 quarters.
  • Two Sigma Advisers's State Street SPDR S&P Biotech ETF position peaked at $133M in Q1 2023.
  • 738 funds tracked by Wall St. Rank held State Street SPDR S&P Biotech ETF as of Q4 2024.

Based on Two Sigma Advisers's 13F filing for Q4 2024, filed 14 Feb 2025.