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SPDR S&P Biotech ETF
XBI

Overview Fund Activity

698 hedge funds and large institutions have $7.55B invested in SPDR S&P Biotech ETF in 2021 Q4 according to their latest regulatory filings, with 139 funds opening new positions, 210 increasing their positions, 198 reducing their positions, and 63 closing their positions.

Holders
698
Holders Change
+66
Holders Change %
+10.44%
% of All Funds
10.78%
Holding in Top 10
20
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.31%
New
139
Increased
210
Reduced
198
Closed
63
Calls
$2.63B
Puts
$3.35B
Net Calls
-$719M
Net Calls Change
+$1.05B

Top Buyers

1
BC
1
Boxer Capital
California
$246M
2
Bank of Nova Scotia
2
Bank of Nova Scotia
Ontario, Canada
$196M
3
Jane Street
3
Jane Street
New York
$281M
4
MCM
4
Moore Capital Management
New York
$150M
5
Goldman Sachs
5
Goldman Sachs
New York
$905M

Top Sellers

1
BNP Paribas Financial Markets
1
BNP Paribas Financial Markets
France
$127M
2
JPMorgan Chase & Co
2
JPMorgan Chase & Co
New York
$24.4M
3
Toronto Dominion Bank
3
Toronto Dominion Bank
Ontario, Canada
$346M
4
Bank of America
4
Bank of America
North Carolina
$489M
5
CAC
5
Cowen and Company
New York
$0
Name Market Value Shares Shares
Change 		Shares
Change %
Goldman Sachs
1
Goldman Sachs
New York
$905M 8,083,203 +1,229,149 +18%
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
2
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
Ontario, Canada
$594M 5,305,000 +400,000 +8%
Bank of America
3
Bank of America
North Carolina
$489M 4,367,894 -1,635,755 -27%
Citigroup
4
Citigroup
New York
$408M 3,640,857 +997,524 +38%
Toronto Dominion Bank
5
Toronto Dominion Bank
Ontario, Canada
$346M 3,094,035 -1,975,500 -39%
Morgan Stanley
6
Morgan Stanley
New York
$343M 3,060,040 -256,088 -8%
UBS Group
7
UBS Group
Switzerland
$286M 2,555,252 +1,085,449 +74%
Jane Street
8
Jane Street
New York
$281M 2,508,875 +1,500,588 +149%
BC
9
Boxer Capital
California
$246M 2,200,000 +2,200,000 New
Barclays
10
Barclays
United Kingdom
$217M 1,938,039 +63,916 +3%
Bank of Nova Scotia
11
Bank of Nova Scotia
Ontario, Canada
$196M 1,750,000 +1,750,000 New
MCM
12
Moore Capital Management
New York
$150M 1,335,600 +1,335,600 New
Canada Pension Plan Investment Board
13
Canada Pension Plan Investment Board
Ontario, Canada
$134M 1,200,000 +800,000 +200%
BNP Paribas Financial Markets
14
BNP Paribas Financial Markets
France
$127M 1,131,425 -4,082,782 -78%
ACA
15
Avoro Capital Advisors
New York
$118M 1,050,000 +1,050,000 New
O
16
OrbiMed
New York
$113M 1,009,700 -56,000 -5%
CI
17
Clal Insurance
Israel
$94.9M 848,000 +276,650 +48%
Wells Fargo
18
Wells Fargo
California
$91.2M 814,793 -132,615 -14%
PF
19
Phoenix Financial
Israel
$89.5M 799,505 +231,855 +41%
Bank Julius Baer & Co
20
Bank Julius Baer & Co
Switzerland
$81.6M 728,810 +165,265 +29%
Thrivent Financial for Lutherans
21
Thrivent Financial for Lutherans
Minnesota
$65.4M 584,236 -74,409 -11%
LPL Financial
22
LPL Financial
California
$64.7M 578,115 +42,152 +8%
Royal Bank of Canada
23
Royal Bank of Canada
Ontario, Canada
$61.8M 551,934 +135,797 +33%
HT
24
HAP Trading
New York
$60.9M 543,830 +543,830 New
Two Sigma Advisers
25
Two Sigma Advisers
New York
$59.5M 531,600 +531,600 New
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